J
Julie C. Price
Researcher at Harvard University
Publications - 271
Citations - 28129
Julie C. Price is an academic researcher from Harvard University. The author has contributed to research in topics: Pittsburgh compound B & Cerebral blood flow. The author has an hindex of 71, co-authored 252 publications receiving 25567 citations. Previous affiliations of Julie C. Price include University of Pittsburgh.
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Journal ArticleDOI
Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B.
William E. Klunk,Henry Engler,Agneta Nordberg,Yanming Wang,G. Blomqvist,Daniel P. Holt,Mats Bergström,Irina Savitcheva,Guo Feng Huang,Sergio Estrada,Birgitta Ausén,Manik L. Debnath,Julien Barletta,Julie C. Price,Johan Sandell,Brian J. Lopresti,Anders Wall,Pernilla Koivisto,Gunnar Antoni,Chester A. Mathis,Bengt Långström +20 more
TL;DR: The results suggest that PET imaging with the novel tracer, PIB, can provide quantitative information on amyloid deposits in living subjects.
Journal ArticleDOI
Consensus nomenclature for in vivo imaging of reversibly binding radioligands
Robert B. Innis,Vincent J. Cunningham,Jacques Delforge,Masahiro Fujita,Albert Gjedde,Roger N. Gunn,James E. Holden,Sylvain Houle,Sung-Cheng Huang,Masanori Ichise,Hidehiro Iida,Hiroshi Ito,Yuichi Kimura,Robert A. Koeppe,Gitte M. Knudsen,Juhani Knuuti,Adriaan A. Lammertsma,Marc Laruelle,Jean Logan,Ralph Paul Maguire,Mark A. Mintun,Evan D. Morris,Ramin V. Parsey,Julie C. Price,Mark Slifstein,Vesna Sossi,Tetsuya Suhara,John R. Votaw,Dean F. Wong,Richard E. Carson +29 more
TL;DR: An international group of experts in pharmacokinetic modeling recommends a consensus nomenclature to describe in vivo molecular imaging of reversibly binding radioligands.
Journal ArticleDOI
Imaging beta-amyloid burden in aging and dementia.
Christopher C. Rowe,Steven Ng,Uwe Ackermann,Sylvia J. Gong,Kerryn E. Pike,Gregory Raymond Savage,Tiffany F. Cowie,Kerryn L Dickinson,Paul Maruff,David Darby,Clare Smith,Michael Woodward,John Merory,Henri Tochon-Danguy,Graeme O'Keefe,William E. Klunk,Chett A Mathis,Julie C. Price,Colin L. Masters,Colin L. Masters,Victor L. Villemagne,Victor L. Villemagne +21 more
TL;DR: Pittsburgh Compound B PET findings match histopathologic reports of β-amyloid (Aβ) distribution in aging and dementia, and suggest that Aβ may influence the development of dementia with Lewy bodies, and therefore strategies to reduce A β may benefit this condition.
Journal ArticleDOI
Frequent Amyloid Deposition Without Significant Cognitive Impairment Among the Elderly
Howard J. Aizenstein,Robert D. Nebes,Judith Saxton,Julie C. Price,Chester A. Mathis,Nicholas D. Tsopelas,Scott K. Ziolko,Jeffrey A. James,Beth E. Snitz,Patricia R. Houck,Wenzhu Bi,Ann D. Cohen,Brian J. Lopresti,Steven T. DeKosky,Edythe M. Halligan,William E. Klunk +15 more
TL;DR: In this group of participants without clinically significant impairment, amyloid deposition was not associated with worse cognitive function, suggesting that an elderly person with a significantAmyloid burden can remain cognitively normal, but this finding is based on relatively small numbers and needs to be replicated in larger cohorts.
Journal ArticleDOI
Post-mortem Correlates of in Vivo PiB-PET Amyloid Imaging in a Typical Case of Alzheimer's Disease
Milos D. Ikonomovic,William E. Klunk,Eric E. Abrahamson,Chester A. Mathis,Julie C. Price,Nicholas D. Tsopelas,Brian J. Lopresti,Scott K. Ziolko,Wenzhu Bi,William R. Paljug,Manik L. Debnath,Caroline E. Hope,Barbara A. Isanski,Ronald L. Hamilton,Steven T. DeKosky +14 more
TL;DR: In the Alzheimer's disease subject who underwent PiB-PET prior to death, in vivo PiB retention levels correlated directly with region-matched post-mortem measures of [3H]PiB binding, insoluble Aβ peptide levels, 6-CN-PiB- and Aβ plaque load, but not with measures of NFT.