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Kentaro Hayashi

Researcher at Nagasaki University

Publications -  173
Citations -  3486

Kentaro Hayashi is an academic researcher from Nagasaki University. The author has contributed to research in topics: Aneurysm & Internal carotid artery. The author has an hindex of 28, co-authored 154 publications receiving 2983 citations. Previous affiliations of Kentaro Hayashi include University of Kentucky.

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Effects of Extracranial–Intracranial Bypass for Patients With Hemorrhagic Moyamoya Disease: Results of the Japan Adult Moyamoya Trial

TL;DR: Although statistically marginal, Kaplan–Meier analysis revealed the significant difference between surgical and nonsurgical group, suggesting the preventive effect of direct bypass against rebleeding.
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Pericytes from brain microvessels strengthen the barrier integrity in primary cultures of rat brain endothelial cells.

TL;DR: The influence of pericytes on the BBB properties of brain endothelial cells may be as important as that of astrocytes and could be exploited in the construction of better BBB models.
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MiR-195, miR-455-3p and miR-10a* are implicated in acquired temozolomide resistance in glioblastoma multiforme cells

TL;DR: Those miRNAs may play a role in acquired TMZ resistance and could be a novel target for recurrent GBM treatment, as suggested by in silico analysis combined with cDNA microarray experiment.
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Effects of hypoxia on endothelial/pericytic co-culture model of the blood-brain barrier.

TL;DR: Despite hypoxia-induced disruption of the barrier in endothelial monolayer and non-contact co-culture models, a minimum of dysfunction was seen in the contact co- culture model, so it is considered that pericytes effect on the endothelia by secreting factors or through a gap junction.
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The NMDA and AMPA/KA receptors are involved in glutamate-induced alterations of occludin expression and phosphorylation in brain endothelial cells.

TL;DR: Findings indicate the opposite effects of the NMDA and AMPA/KA receptors on occludin phosphorylation and disruption of the BBB functions.