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Kevin P. Francis
Researcher at PerkinElmer
Publications - 78
Citations - 4121
Kevin P. Francis is an academic researcher from PerkinElmer. The author has contributed to research in topics: Population & In vivo. The author has an hindex of 30, co-authored 73 publications receiving 3630 citations.
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Journal ArticleDOI
Bacillus weihenstephanensis sp. nov. is a new psychrotolerant species of the Bacillus cereus group.
Sabine Lechner,Ralf Mayr,Kevin P. Francis,B. M. Prüss,T. Kaplan,E. Wiessner-Gunkel,Gordon S. A. B. Stewart,Siegfried Scherer +7 more
TL;DR: The DNA sequences investigated exhibited a high degree of sequence similarity indicating a close relationship between the species of the B. cereus group, and strongly support a hitherto unrecognized fifth sub-group within the B.'s cereus species group comprising psychrotolerant, but not mesophilic, B. mycoides strains.
Journal ArticleDOI
Monitoring bioluminescent Staphylococcus aureus infections in living mice using a novel luxABCDE construct.
Kevin P. Francis,Danny Joh,Carolyn Bellinger-Kawahara,Matthew J. Hawkinson,Tony Purchio,Pamela R. Contag +5 more
TL;DR: This paper shows for the first time that bioluminescence offers a method for monitoring S. aureus infections in vivo that is sensitive and noninvasive and requires fewer animals than conventional methodologies.
Journal ArticleDOI
Microbiota of Human Breast Tissue
Camilla Urbaniak,Camilla Urbaniak,Joanne Cummins,Muriel Brackstone,Jean M. Macklaim,Jean M. Macklaim,Gregory B. Gloor,Chwanrow K. Baban,Leslie Scott,Deidre M. O'Hanlon,Jeremy P. Burton,Kevin P. Francis,Mark Tangney,Gregor Reid,Gregor Reid +14 more
TL;DR: A diverse population of bacteria was detected within tissue collected from sites all around the breast in women aged 18 to 90, not all of whom had a history of lactation, and the principal phylum was Proteobacteria.
Journal ArticleDOI
Extracellular replication of Listeria monocytogenes in the murine gall bladder.
Jonathan Hardy,Kevin P. Francis,Monica DeBoer,Pauline Chu,Karine A. Gibbs,Christopher H. Contag +5 more
TL;DR: In vivo bioluminescence imaging was employed to determine the location of the infection over time in live animals, revealing strong signals from the gall bladder over a period of several days, in diseased as well as asymptomatic animals and suggesting that L. monocytogenes may be carried in the human gall bladder.
Journal ArticleDOI
Real-time in vivo imaging of invasive- and biomaterial-associated bacterial infections using fluorescently labelled vancomycin
Marleen van Oosten,Marleen van Oosten,Tina Schäfer,Joost A. C. Gazendam,Knut Ohlsen,Eleni Tsompanidou,Marcus C. de Goffau,Hermie J. M. Harmsen,Lucia M. A. Crane,Ed Lim,Kevin P. Francis,Lael Cheung,Michael Olive,Vasilis Ntziachristos,Jan Maarten van Dijl,Gooitzen M. van Dam +15 more
TL;DR: It is concluded that vanco-800CW has a high potential for enhanced non-invasive diagnosis of infections with Gram-positive bacteria and is a promising candidate for early-phase clinical trials.