K
Kevin R. West
Researcher at University of Cambridge
Publications - 26
Citations - 2369
Kevin R. West is an academic researcher from University of Cambridge. The author has contributed to research in topics: Dynamic combinatorial chemistry & Derivative (chemistry). The author has an hindex of 15, co-authored 26 publications receiving 2196 citations.
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Journal ArticleDOI
Dynamic combinatorial chemistry.
Peter T. Corbett,Julien Leclaire,Laurent Vial,Kevin R. West,Jean-Luc Wietor,Jeremy K. M. Sanders,Sijbren Otto +6 more
Journal ArticleDOI
Reversible Covalent Chemistry in Drug Delivery
Kevin R. West,Sijbren Otto +1 more
TL;DR: This review focuses on the chemistry that underlies two types of cleavable covalent bonds that are frequently used to link drugs to their various carriers: disulfide bonds and hydrazone bonds.
Journal ArticleDOI
Dynamic Combinatorial Libraries of Disulfide Cages in Water
TL;DR: DCLs containing water-soluble disulfide-linked cages (alongside macrocyclic structures) have been generated and characterized, and the diversity of the cages generated opens new possibilities for a generalized combinatorial strategy toward molecular encapsulation.
Journal ArticleDOI
Thin Films of Molybdenum Disulfide Doped with Chromium by Aerosol-Assisted Chemical Vapor Deposition (AACVD)
David J. Lewis,Aleksander A. Tedstone,Xiang Li Zhong,Edward A. Lewis,A. P. Rooney,Nicky Savjani,Jack R. Brent,Sarah J. Haigh,M. Grace Burke,Christopher A. Muryn,James Raftery,Chris P. Warrens,Kevin R. West,Sander Gaemers,Paul O'Brien +14 more
TL;DR: A combined single-source precursor approach has been developed for the deposition of thin films of Cr-doped molybdenum disulfide (MoS2) by aerosol-assisted chemical vapor deposition (AACVD).
Journal ArticleDOI
Dynamic combinatorial discovery of a [2]-catenane and its guest-induced conversion into a molecular square host.
Kevin R. West,R. Fred Ludlow,Peter T. Corbett,Pol Besenius,Friederike M. Mansfeld,Peter A. G. Cormack,David C. Sherrington,Jonathan M. Goodman,Marc C. A. Stuart,Sijbren Otto +9 more
TL;DR: A simple water-soluble naphthalenedithiol building block is converted quantitatively into a series of octameric [2]-catenanes, composed of two interlocked molecular squares, which disassemble into their macrocyclic components that bind the guest with nanomolar affinity in water.