K
Kewal Kumar Mahapatra
Researcher at National Institute of Technology, Rourkela
Publications - 26
Citations - 676
Kewal Kumar Mahapatra is an academic researcher from National Institute of Technology, Rourkela. The author has contributed to research in topics: Autophagy & Mitophagy. The author has an hindex of 10, co-authored 24 publications receiving 307 citations.
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The emerging, multifaceted role of mitophagy in cancer and cancer therapeutics.
Debasna P. Panigrahi,Prakash Priyadarshi Praharaj,Chandra Sekhar Bhol,Kewal Kumar Mahapatra,Srimanta Patra,Bishnu Prasad Behera,Soumya Ranjan Mishra,Sujit K. Bhutia +7 more
TL;DR: The present review sheds some light on the role of mitophagy in stemness and differentiation during the transition of cell's fate, which could have a crucial role in cancer progression and metastasis.
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Autophagy-modulating phytochemicals in cancer therapeutics: Current evidences and future perspectives.
Srimanta Patra,Soumya Ranjan Mishra,Bishnu Prasad Behera,Kewal Kumar Mahapatra,Debasna P. Panigrahi,Chandra Sekhar Bhol,Prakash Priyadarshi Praharaj,Gautam Sethi,Samir Kumar Patra,Sujit K. Bhutia +9 more
TL;DR: Diverse implicit mechanisms deployed by the bioactive compounds in diagnosis and therapeutics approach during cancer progression with special insight into autophagic regulation are discussed.
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Plant lectins in cancer therapeutics: Targeting apoptosis and autophagy-dependent cell death.
Sujit K. Bhutia,Prashanta Kumar Panda,Niharika Sinha,Prakash Priyadarshi Praharaj,Chandra Sekhar Bhol,Debasna P. Panigrahi,Kewal Kumar Mahapatra,Sarbari Saha,Srimanta Patra,Soumya Ranjan Mishra,Bishnu Prasad Behera,Shankargouda Patil,Tapas K. Maiti +12 more
TL;DR: Although the application of plant lectins in cancer is still in very preliminary stage, advanced high-throughput technology could pave the way for the development of lectin-based complimentary medicine for cancer treatment.
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Intricate role of mitochondrial lipid in mitophagy and mitochondrial apoptosis: its implication in cancer therapeutics.
Prakash Priyadarshi Praharaj,Prajna Paramita Naik,Debasna P. Panigrahi,Chandra Sekhar Bhol,Kewal Kumar Mahapatra,Srimanta Patra,Gautam Sethi,Sujit K. Bhutia +7 more
TL;DR: By targeting mitochondrial lipids in cancer cells, the detailed mechanism linked to drug resistance can be unraveled and the current knowledge about the multifaceted role of mitochondrial lipid in regulating mitophagy and mitochondrial apoptosis is discussed.
Journal ArticleDOI
Mitochondrial dysfunction as a driver of NLRP3 inflammasome activation and its modulation through mitophagy for potential therapeutics.
Soumya Ranjan Mishra,Kewal Kumar Mahapatra,Bishnu Prasad Behera,Srimanta Patra,Chandra Sekhar Bhol,Debasna P. Panigrahi,Prakash Priyadarshi Praharaj,Amruta Singh,Shankargouda Patil,Rohan Dhiman,Sujit K. Bhutia +10 more
TL;DR: In this paper, the NLR family pyrin domain containing 3 (NLRP3) inflammasome is responsible for the sensation of various pathogenic and nonpathogenic damage signals and has a vital role in neuroinflammation and neural diseases.