K
Kimberly A. Homan
Researcher at Wyss Institute for Biologically Inspired Engineering
Publications - 59
Citations - 6611
Kimberly A. Homan is an academic researcher from Wyss Institute for Biologically Inspired Engineering. The author has contributed to research in topics: Molecular imaging & Organoid. The author has an hindex of 23, co-authored 55 publications receiving 5312 citations. Previous affiliations of Kimberly A. Homan include Massachusetts Institute of Technology & University of Texas at Austin.
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Journal ArticleDOI
3D Bioprinting of Vascularized, Heterogeneous Cell‐Laden Tissue Constructs
David B. Kolesky,Ryan L. Truby,A. Sydney Gladman,Travis Alexander Busbee,Kimberly A. Homan,Jennifer A. Lewis +5 more
TL;DR: A new bioprinting method is reported for fabricating 3D tissue constructs replete with vasculature, multiple types of cells, and extracellular matrix that open new -avenues for drug screening and fundamental studies of wound healing, angiogenesis, and stem-cell niches.
Journal ArticleDOI
Three-dimensional bioprinting of thick vascularized tissues.
TL;DR: A multimaterial 3D bioprinting method is reported that enables the creation of thick human tissues (>1 cm) replete with an engineered extracellular matrix, embedded vasculature, and multiple cell types that can be actively perfused for long durations.
Journal ArticleDOI
Bioprinting of 3D Convoluted Renal Proximal Tubules on Perfusable Chips
Kimberly A. Homan,David B. Kolesky,Mark A. Skylar-Scott,Jessica Herrmann,Humphrey Obuobi,Annie Moisan,Jennifer A. Lewis +6 more
TL;DR: A bioprinting method is reported for creating 3D human renal proximal tubules in vitro that are fully embedded within an extracellular matrix and housed in perfusable tissue chips, allowing them to be maintained for greater than two months.
Journal ArticleDOI
Flow-enhanced vascularization and maturation of kidney organoids in vitro.
Kimberly A. Homan,Navin Gupta,Navin Gupta,Katharina T. Kroll,David B. Kolesky,Mark A. Skylar-Scott,Tomoya Miyoshi,Donald Mau,M. Todd Valerius,M. Todd Valerius,Thomas C. Ferrante,Joseph V. Bonventre,Joseph V. Bonventre,Jennifer A. Lewis,Jennifer A. Lewis,Ryuji Morizane,Ryuji Morizane +16 more
TL;DR: An in vitro method for culturing kidney organoids under flow on millifluidic chips is reported, which expands their endogenous pool of endothelial progenitor cells and generates vascular networks with perfusable lumens surrounded by mural cells.
Journal ArticleDOI
Silica-Coated Gold Nanorods as Photoacoustic Signal Nanoamplifiers
Yun Sheng Chen,Wolfgang Frey,Seungsoo Kim,Pieter Kruizinga,Kimberly A. Homan,Stanislav Emelianov +5 more
TL;DR: The results suggest that the enhancement is caused by the reduction of the gold interfacial thermal resistance with the solvent due to the silica coating, and shows that these hybrid particles acting as "photoacoustic nanoamplifiers" are high efficiency contrast agents for photoac acoustic imaging or photoacoustic image-guided therapy.