Journal ArticleDOI
3D Bioprinting of Vascularized, Heterogeneous Cell‐Laden Tissue Constructs
David B. Kolesky,Ryan L. Truby,A. Sydney Gladman,Travis Alexander Busbee,Kimberly A. Homan,Jennifer A. Lewis +5 more
TLDR
A new bioprinting method is reported for fabricating 3D tissue constructs replete with vasculature, multiple types of cells, and extracellular matrix that open new -avenues for drug screening and fundamental studies of wound healing, angiogenesis, and stem-cell niches.Abstract:
A new bioprinting method is reported for fabricating 3D tissue constructs replete with vasculature, multiple types of cells, and extracellular matrix. These intricate, heterogeneous structures are created by precisely co-printing multiple materials, known as bioinks, in three dimensions. These 3D micro-engineered environments open new -avenues for drug screening and fundamental studies of wound healing, angiogenesis, and stem-cell niches.read more
Citations
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Journal ArticleDOI
Synthesis, properties, and biomedical applications of gelatin methacryloyl (GelMA) hydrogels
Kan Yue,Kan Yue,Grissel Trujillo-de Santiago,Grissel Trujillo-de Santiago,Mario Moises Alvarez,Ali Tamayol,Ali Tamayol,Nasim Annabi,Nasim Annabi,Nasim Annabi,Ali Khademhosseini,Ali Khademhosseini,Ali Khademhosseini +12 more
TL;DR: Gelatin methacryloyl (GelMA) hydrogels have been widely used for various biomedical applications due to their suitable biological properties and tunable physical characteristics and are demonstrated in a wide range of tissue engineering applications including engineering of bone, cartilage, cardiac, and vascular tissues, among others.
Journal ArticleDOI
Advances in engineering hydrogels
TL;DR: The advances in making hydrogels with improved mechanical strength and greater flexibility for use in a wide range of applications are reviewed, foreseeing opportunities in the further development of more sophisticated fabrication methods that allow better-controlled hydrogel architecture across multiple length scales.
Journal ArticleDOI
An integrated design and fabrication strategy for entirely soft, autonomous robots
Michael Wehner,Michael Wehner,Ryan L. Truby,Ryan L. Truby,Daniel J. Fitzgerald,Daniel J. Fitzgerald,Bobak Mosadegh,Bobak Mosadegh,George M. Whitesides,George M. Whitesides,Jennifer A. Lewis,Jennifer A. Lewis,Robert J. Wood,Robert J. Wood +13 more
TL;DR: An untethered operation of a robot composed solely of soft materials that autonomously regulates fluid flow and, hence, catalytic decomposition of an on-board monopropellant fuel supply is reported.
Journal ArticleDOI
Three-dimensional printing of complex biological structures by freeform reversible embedding of suspended hydrogels.
Thomas J. Hinton,Quentin Jallerat,Rachelle N. Palchesko,Joon Hyung Park,Martin S. Grodzicki,Hao Jan Shue,Mohamed H. Ramadan,Andrew Hudson,Adam W. Feinberg +8 more
TL;DR: Three-dimensional structures based on femurs, branched coronary arteries, trabeculated embryonic hearts, and human brains were mechanically robust and recreated complex 3D internal and external anatomical architectures.
Journal ArticleDOI
3D Bioprinting Human Chondrocytes with Nanocellulose-Alginate Bioink for Cartilage Tissue Engineering Applications
Kajsa Markstedt,Athanasios Mantas,Ivan Tournier,Héctor Martínez Ávila,Daniel Hägg,Paul Gatenholm +5 more
TL;DR: A bioink that combines the outstanding shear thinning properties of nanofibrillated cellulose (NFC) with the fast cross-linking ability of alginate with the potential use of nanocellulose for 3D bioprinting of living tissues and organs is formulated.
References
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Book
Molecular Cell Biology
TL;DR: Molecular cell biology, Molecular cell biology , مرکز فناوری اطلاعات و اصاع رسانی, کδاوρزی
Journal ArticleDOI
Scaffolds in tissue engineering bone and cartilage.
TL;DR: Research on the tissue engineering of bone and cartilage from the polymeric scaffold point of view is reviews from a biodegradable and bioresorbable perspective.
Journal ArticleDOI
Porous scaffold design for tissue engineering
TL;DR: The integration of CTD with SFF to build designer tissue-engineering scaffolds is reviewed and the mechanical properties and tissue regeneration achieved using designer scaffolds are details.
Journal ArticleDOI
Cell-laden microengineered gelatin methacrylate hydrogels.
Jason W. Nichol,Sandeep T. Koshy,Sandeep T. Koshy,Sandeep T. Koshy,Hojae Bae,Hojae Bae,Chang M. Hwang,Chang M. Hwang,Seda Yamanlar,Seda Yamanlar,Ali Khademhosseini,Ali Khademhosseini +11 more
TL;DR: GelMA hydrogels could be useful for creating complex, cell- responsive microtissues, such as endothelialized microvasculature, or for other applications that require cell-responsive microengineered hydrogELs.