Kinga Balogh

TL;DR: A highly sensitive and reproducible SNP‐typing method is established with amplification of all 52 DNA fragments in one PCR reaction followed by detection of the SNPs with two single base extension reactions analysed using CE.

TL;DR: The approach takes advantage of the specific geographic distribution of the Y‐chromosome haplogroups and demonstrates the utility of binary polymorphisms to infer the origin of a male lineage.

TL;DR: Results indicate that, although the ability to successfully type good quality, low copy number extracts is lower, the 52-plex SNP assay performed better than STR typing on degraded samples, and also on samples that were both degraded and of limited quantity, suggesting that SNP analysis can provide advantages over STR analysis in forensically relevant circumstances.

TL;DR: The results of the collaborative exercise on typing of autosomal single nucleotide polymorphisms (SNP) for forensic genetic investigations in crime cases demonstrate that SNP typing with SBE, capillary electrophoresis and multicolour detection methods can be developed for forensic genetics.

TL;DR: To assess the quality of amplified DNA obtained by whole genome amplification, 17 independent STR loci have been typed using two multiplex kits and results have been compared for correct genotypes, heterozygous peak balance and allelic dropout.