K
Kitaru Suda
Researcher at University of Basel
Publications - 27
Citations - 2619
Kitaru Suda is an academic researcher from University of Basel. The author has contributed to research in topics: Saccharomyces cerevisiae & Yeast. The author has an hindex of 25, co-authored 27 publications receiving 2551 citations.
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Journal ArticleDOI
Requirement for the yeast gene LON in intramitochondrial proteolysis and maintenance of respiration
TL;DR: The role of protein degradation in mitochondrial homeostasis was explored by cloning of a gene from Saccharomyces cerevisiae that encodes a protein resembling the adenosine triphosphate (ATP)-dependent bacterial protease Lon, which has a typical mitochondrial matrix-targeting sequence at its amino terminus.
Journal ArticleDOI
ATP-dependent proteases that also chaperone protein biogenesis
Carolyn K. Suzuki,Martijn Rep,van Jan Maarten Dijl,Kitaru Suda,Leslie A. Grivell,Gottfried Schatz +5 more
TL;DR: The ATP-dependent proteases Clp and FTSH from bacteria, as well as mitochondrial homologs of FtsH and Lon from yeast, may act as chaperones; they mediate not only proteolysis, but also the insertion of proteins into membranes and the disassembly or oligomerization of protein complexes.
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Bacterial Na+‐ATP synthase has an undecameric rotor
Henning Stahlberg,Daniel J. Müller,Daniel J. Müller,Kitaru Suda,Dimitrios Fotiadis,Andreas Engel,Thomas Meier,Ulrich Matthey,Peter Dimroth +8 more
TL;DR: The rotor stoichiometry of Ilyobacter tartaricus ATP synthase is determined by atomic force microscopy and cryo‐electron microscopy, and shows the cylindrical sodium‐driven rotor to comprise 11 c‐subunits.
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Reconstitution of the initial steps of mitochondrial protein import
TL;DR: The ATP- mediated transfer of a precursor from MSF to specific subunits of the import receptor is similar to the GTP-mediated transfer of precursors from the signal recognition particle to its receptor on the endoplasmic reticulum.
Journal ArticleDOI
Promotion of Mitochondrial Membrane Complex Assembly by a Proteolytically Inactive Yeast Lon
Martijn Rep,van Jan Maarten Dijl,Kitaru Suda,Gottfried Schatz,Leslie A. Grivell,Carolyn K. Suzuki +5 more
TL;DR: It is suggested that the mitochondrial proteases Lon, Afg3p, and Rca1p can also serve a chaperone-like function in the assembly of mitochondrial protein complexes.