D
Daniel J. Müller
Researcher at ETH Zurich
Publications - 392
Citations - 29298
Daniel J. Müller is an academic researcher from ETH Zurich. The author has contributed to research in topics: Force spectroscopy & Membrane protein. The author has an hindex of 88, co-authored 359 publications receiving 25733 citations. Previous affiliations of Daniel J. Müller include Deutsche Forschungsgemeinschaft & University of Basel.
Papers
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Journal ArticleDOI
GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death
Lorenzo Sborgi,Sebastian Rühl,Estefania Mulvihill,Joka Pipercevic,Rosalie Heilig,Henning Stahlberg,Christopher J. Farady,Daniel J. Müller,Petr Broz,Sebastian Hiller +9 more
TL;DR: Overall, these data demonstrate that GSDMD is the direct and final executor of pyroptotic cell death.
Journal ArticleDOI
Tensile forces govern germ-layer organization in zebrafish
Michael Krieg,Y. Arboleda-Estudillo,Y. Arboleda-Estudillo,Pierre-Henri Puech,Jos Käfer,François Graner,Daniel J. Müller,Carl-Philipp Heisenberg +7 more
TL;DR: It is shown that differential actomyosin-dependent cell-cortex tension, regulated by Nodal/TGFβ-signalling (transforming growth factor β), constitutes a key factor that directs progenitor-cell sorting in germ-layer organization during gastrulation.
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Atomic force microscopy as a multifunctional molecular toolbox in nanobiotechnology
Daniel J. Müller,Yves F. Dufrêne +1 more
TL;DR: In this paper, the authors review the fascinating opportunities offered by the rapid advances in atomic force microscopy (AFM) and highlight the potential of AFM for medical diagnostics and environmental monitoring.
Journal ArticleDOI
Unfolding pathways of individual bacteriorhodopsins.
Filipp Oesterhelt,Dieter Oesterhelt,Matthias Pfeiffer,Andreas Engel,Hermann E. Gaub,Daniel J. Müller +5 more
TL;DR: Atomic force microscopy and single-molecule force spectroscopy were combined to image and manipulate purple membrane patches from Halobacterium salinarum, revealing the individuality of the unfolding pathways.
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Imaging modes of atomic force microscopy for application in molecular and cell biology
Yves F. Dufrêne,Toshio Ando,Ricardo Garcia,David Alsteens,David Martinez-Martin,Andreas Engel,Christoph Gerber,Daniel J. Müller +7 more
TL;DR: The basic principles, advantages and limitations of the most common AFM bioimaging modes are reviewed, including the popular contact and dynamic modes, as well as recently developed modes such as multiparametric, molecular recognition, multifrequency and high-speed imaging.