K
Klaus Wienhard
Researcher at Max Planck Society
Publications - 149
Citations - 8640
Klaus Wienhard is an academic researcher from Max Planck Society. The author has contributed to research in topics: Cerebral blood flow & Positron emission tomography. The author has an hindex of 50, co-authored 149 publications receiving 8446 citations.
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Journal ArticleDOI
The Ecat Exact Hr - Performance of a New High-resolution Positron Scanner
Klaus Wienhard,Magnus Dahlbom,Lars Eriksson,Christian Michel,T. Bruckbauer,Uwe Pietrzyk,Wolf-Dieter Heiss +6 more
TL;DR: Due to its special properties, the ECAT EXACT HR can be equally applied to routine clinical brain and whole-body imaging and to noninvasive experimental studies of regional tracer concentrations in medium-sized animals.
Journal ArticleDOI
Progressive derangement of periinfarct viable tissue in ischemic stroke.
Wolf-Dieter Heiss,Michael Huber,Gereon R. Fink,Karl Herholz,Uwe Pietrzyk,Rainer Wagner,Klaus Wienhard +6 more
TL;DR: Evidence of viable tissue in the border zone of ischemia up to 48 h after stroke is furnished, while this viable peri-infarct tissue exhibits some potential for effective treatment of ischemic stroke.
Journal ArticleDOI
The ECAT HRRT: performance and first clinical application of the new high resolution research tomograph
Klaus Wienhard,Matthias J. Schmand,Michael E. Casey,K. Baker,J. Bao,L. Eriksson,W. F. Jones,C. Knoess,Mark Lenox,Martin J. Lercher,P. Luk,C. Michel,J. Reed,Norbert Richerzhagen,J.T. Treffert,Stefan Vollmar,J.W. Young,W.-D. Heiss,R. Nutt +18 more
TL;DR: Several issues that have been adequately solved for older generation scanners demand new attention for the ECAT HRRT, like acquiring and handling large amounts of data effectively, strategies for optimal reconstruction, shielding, and correction of random coincidences.
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11C-methionine PET for differential diagnosis of low-grade gliomas
Karl Herholz,T. Hölzer,Bernd Bauer,Rolf Schröder,Juergen Voges,R. I. Ernestus,G. Mendoza,Gerald Weber-Luxenburger,J. Löttgen,Alexander Thiel,Klaus Wienhard,W.-D. Heiss +11 more
TL;DR: The high sensitivity of 11C-methionine uptake for functional endothelial or blood-brain barrier changes suggests that this tracer is particularly useful for evaluation and follow-up of low-grade gliomas.
Journal ArticleDOI
Positron-emission tomography of vector-mediated gene expression in gene therapy for gliomas.
Andreas H. Jacobs,Juergen Voges,Regina Reszka,Martin J. Lercher,Axel Gossmann,Lutz W. Kracht,Ch Kaestle,Rainer Wagner,Klaus Wienhard,W.-D. Heiss +9 more
TL;DR: The extent of HSV-1-tk gene expression seemed to predict the therapeutic response, and the expression of an exogenous gene introduced by gene therapy into patients with gliomas can be monitored non-invasively by PET.