K
Koji Umezawa
Researcher at Shinshu University
Publications - 32
Citations - 377
Koji Umezawa is an academic researcher from Shinshu University. The author has contributed to research in topics: Myocyte & Chemistry. The author has an hindex of 8, co-authored 29 publications receiving 276 citations. Previous affiliations of Koji Umezawa include Osaka University & Tokyo University of Pharmacy and Life Sciences.
Papers
More filters
Journal ArticleDOI
Theory for trivial trajectory parallelization of multicanonical molecular dynamics and application to a polypeptide in water
Jinzen Ikebe,Koji Umezawa,Narutoshi Kamiya,Takanori Sugihara,Yasushige Yonezawa,Yu Takano,Haruki Nakamura,Junichi Higo +7 more
TL;DR: The current method is suitable for conformational sampling of a large system to reduce the waiting time to obtain a canonical ensemble statistically reliable and produces the free‐energy landscape considerably faster than a single‐run McMD does.
Journal ArticleDOI
Hydrophobic Surface Enhances Electrostatic Interaction in Water
TL;DR: It is demonstrated that electrostatic interaction in water is actually strengthened near the hydrophobic surface, due to both the decreased water density and the reduced water dipole correlation in the direction perpendicular to the surface.
Journal ArticleDOI
A virtual-system coupled multicanonical molecular dynamics simulation: Principles and applications to free-energy landscape of protein–protein interaction with an all-atom model in explicit solvent
TL;DR: A novel generalized ensemble method, a virtual-system coupled multicanonical molecular dynamics (V-McMD), to enhance conformational sampling of biomolecules expressed by an all-atom model in an explicit solvent.
Journal ArticleDOI
Distinct cell proliferation, myogenic differentiation, and gene expression in skeletal muscle myoblasts of layer and broiler chickens
Yuma Nihashi,Koji Umezawa,Sayaka Shinji,Yu Hamaguchi,Hisato Kobayashi,Hisato Kobayashi,Tomohiro Kono,Tamao Ono,Hiroshi Kagami,Tomohide Takaya +9 more
TL;DR: The results present a new perspective that the opioids present in feeds may influence muscle development of domestic animals and experimentally proved that one of the candidates, enkephalin, an opioid peptide, suppresses myoblast growth.
Journal ArticleDOI
Epicatechin oligomers longer than trimers have anti-cancer activities, but not the catechin counterparts
Kohki Takanashi,Manato Suda,Kiriko Matsumoto,Chisato Ishihara,Kazuya Toda,Koichiro Kawaguchi,Shogo Senga,Narumi Kobayashi,Mikihiro Ichikawa,Miyuki Katoh,Yasunao Hattori,Sei-ichi Kawahara,Koji Umezawa,Hiroshi Fujii,Hidefumi Makabe +14 more
TL;DR: Synthetic studies clearly demonstrate that epicatechin oligomers longer than trimers have significant anti-tumorigenic activities, but not the catechin counterparts.