Konstantinos Liaras

TL;DR: Evaluation of antibacterial activity showed that almost all the compounds exhibited greater activity than reference drugs and thus could be promising novel drug candidates.

TL;DR: This review focuses on the biological activity of several thiazole and thiazolidinone derivatives as COX-1/COX-2 and LOX inhibitors, which could provide numerous therapeutic advantages in terms of anti-inflammatory activity, improved gastric protection and safer cardiovascular profile compared to conventional NSAIDs.

TL;DR: The synthesis of novel 5-arylidene-2-(1, 3-thiazol-2-ylimino)-1,3- Thiazolidin-4-ones is described, which exhibited better antimicrobial activity than commercial drugs, bifonazole, ketoconazole), ampicillin and streptomycin.

TL;DR: The aim of this review is to describe recent developments in the study of the antioxidant activity of thiazole and thiazolidinone derivatives, which are the core structure in a variety of pharmaceuticals with a broad spectrum of biological activity and their role in preventing the formation of ROS.

TL;DR: Docking studies indicated that DNA gyrase, GyrB and MurA inhibition may explain the antibacterial activity of the novel thiazole-based chalcones.