K
Konstantinos Papaspyrou
Researcher at University of Mainz
Publications - 10
Citations - 370
Konstantinos Papaspyrou is an academic researcher from University of Mainz. The author has contributed to research in topics: Paraganglioma & SDHB. The author has an hindex of 10, co-authored 10 publications receiving 340 citations.
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Journal ArticleDOI
Non-pheochromocytoma (PCC)/paraganglioma (PGL) tumors in patients with succinate dehydrogenase-related PCC-PGL syndromes: a clinicopathological and molecular analysis.
Thomas G. Papathomas,José Gaal,Eleonora P M Corssmit,Lindsey Oudijk,Esther Korpershoek,Ketil Heimdal,Jean-Pierre Bayley,Hans Morreau,Marieke F. van Dooren,Konstantinos Papaspyrou,Thomas Schreiner,Torsten Hansen,Per Arne Andresen,David F. Restuccia,Ingrid van Kessel,Geert J.L.H. van Leenders,Johan M. Kros,Leendert H. J. Looijenga,Leo J. Hofland,Wolf J. Mann,Francien H van Nederveen,Ozgur Mete,Sylvia L. Asa,Ronald R. de Krijger,Winand N.M. Dinjens +24 more
TL;DR: Findings strengthen the etiological association of SDHx genes with pituitary neoplasia and provide evidence against a link between PTC andSDHx mutations.
Journal ArticleDOI
Head and neck paragangliomas: Report of 175 patients (1989–2010)
Konstantinos Papaspyrou,Torsten Mewes,Heidi Rossmann,Christian Fottner,Brigitte Schneider-Raetzke,Oliver Bartsch,Mathias Schreckenberger,Karl J. Lackner,Ronald G. Amedee,Wolf J. Mann +9 more
TL;DR: Attention of the otorhinolaryngologist needs to be drawn to the versatile aspects of head and neck paragangliomas (PGLs).
Journal ArticleDOI
Management of head and neck paragangliomas: Review of 120 patients
TL;DR: Head and neck paragangliomas are rare, mostly benign tumors caused by mutations in the succinate dehydrogenase genes B, C, or D and may appear multifocally.
Journal ArticleDOI
Fascin upregulation in primary head and neck squamous cell carcinoma is associated with lymphatic metastasis.
Konstantinos Papaspyrou,Christoph Brochhausen,Irene Schmidtmann,Kai Fruth,Haralampos Gouveris,James Kirckpatrick,Wolf J. Mann,Juergen Brieger +7 more
TL;DR: The high expression level of fascin in the tumor tissues was correlated with the N-status, however, not with overall survival, therefore, fascin may be a suitable marker for the prediction of regional lymphatic metastasis in HNSCC.
Journal ArticleDOI
Phenotypic variability and risk of malignancy in SDHC-linked paragangliomas: lessons from three unrelated cases with an identical germline mutation (p.Arg133*).
Julia K. Bickmann,Stefanie Sollfrank,Arno Schad,Thomas J. Musholt,Erik Springer,Matthias Miederer,Oliver Bartsch,Konstantinos Papaspyrou,Dimitrios Koutsimpelas,Wolf J. Mann,Matthias M. Weber,Karl J. Lackner,Heidi Rossmann,Christian Fottner +13 more
TL;DR: The present case shows that SDHC germline mutations can have highly variable phenotypes and may cause malignant PGL, although malignancy is probably rare.