Kumiko Satoh

TL;DR: Results indicate that diosmin and hesperidin, both alone and in combination, act as a chemopreventive agent against colon carcinogenesis, and such effects may be partly due to suppression of cell proliferation in the colonic crypts, although precise mechanisms should be clarified.

TL;DR: The modifying effects of two natural products, curcumin and hesperidin, given during the initiation and postinitiation phases of oral carcinogenesis initiated with 4-nitroquinoline 1-oxide (4-NQO) were investigated in male F344 rats and compared with that of beta-carotene as discussed by the authors.

TL;DR: The results indicate that AX and CX are possible chemopreventers for oral carcinogenesis, and such effects may be partly due to suppression of cell proliferation.

TL;DR: Results indicate that the flavonoids chalcone, 2-hydroxychalcone, and quercetin present in daily foods have an inhibitory effect on oral carcinogenesis initiated with 4-NQO, and such a modifying effect may be related partly to the suppression of cell proliferation.

TL;DR: In this article, the modulating effects of dietary feeding of two xanthophylls, astaxanthin (AX) and canthaxantha (CX), during the post-initiation phase on colon carcinogenesis initiated with azoxymethane (AOM) were investigated in male F344 rats.