K
Kunio Shinohara
Researcher at Tokai University
Publications - 57
Citations - 647
Kunio Shinohara is an academic researcher from Tokai University. The author has contributed to research in topics: Microscopy & Microscope. The author has an hindex of 12, co-authored 57 publications receiving 589 citations. Previous affiliations of Kunio Shinohara include Japan Atomic Energy Agency & Institute of Medical Science.
Papers
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Journal ArticleDOI
Contribution of indirect action to radiation-induced mammalian cell inactivation: dependence on photon energy and heavy-ion LET.
Atsushi Ito,Hisako Nakano,Yohsuke Kusano,Ryoichi Hirayama,Yoshiya Furusawa,Chieko Murayama,Tomoyuki Mori,Yosuke Katsumura,Kunio Shinohara +8 more
TL;DR: The inactivation efficiency for indirect action was greater than that for direct action over the photon energy range and the ion LET range tested, and a significant contribution of direct action was also found for the increased RBE in the low photon energy region.
Journal ArticleDOI
X-Ray-Induced Cell Death: Apoptosis and Necrosis
Hisako Nakano,Kunio Shinohara +1 more
TL;DR: The results suggest that apoptosis and necrosis are induced by X rays in a manner which is dependent on the cell line irrespective of the capability of the cells to develop apoptosis.
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Atherosclerotic plaque imaging using phase-contrast X-ray computed tomography
Masakazu Shinohara,Tomoya Yamashita,Hideto Tawa,Masafumi Takeda,Naoto Sasaki,Tomofumi Takaya,Ryuji Toh,Akihisa Takeuchi,Takuji Ohigashi,Kunio Shinohara,Seinosuke Kawashima,Mitsuhiro Yokoyama,Ken-ichi Hirata,Atsushi Momose +13 more
TL;DR: Reliable, noninvasive imaging modalities to characterize plaque components are clinically desirable for detecting unstable coronary plaques, which cause acute coronary syndrome as mentioned in this paper. But these modalities are not suitable for non-invasive diagnosis.
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Application of X-ray microscopy in analysis of living hydrated cells.
TL;DR: Application of two types of X‐ray microscopes, which use laser‐produced plasma X‐rays or synchrotron radiation to image the structure of macrophage cells, is introduced as an example of a novel approach to analysis of biological specimens.
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Effects of Single-pulse (≤ 1 ps) X-rays from Laser-produced Plasmas on Mammalian Cells
TL;DR: There is no increase in the cytotoxic effects of X-rays at dose-rates as high as 10(13) Gy/sec, and it is suggested that the increased cytotoxicity of particle radiation is not attributable to temporally dense ionization.