Chitosan: a versatile biopolymer for orthopaedic tissue-engineering.

https://digital.csic.es/bitstream/10261/63157/4/Gomez-Guillen-collagenreview_CSIC.pdf

Functional and bioactive properties of collagen and gelatin from alternative sources: A review

Chitosan-based formulations for delivery of DNA and siRNA.

Chitin is the world's second most abundant naturally occurring polysaccharide. Much of this is disposed of as waste from seafood crustacean, mainly in shrimps, prawns, crabs, and lobsters, where it occurs as a significant component in the shells/exoskeletons of crustacea. Due to its widespread abundance, its chemical and physical versatility, and the problems of its disposal as a waste material, a wide range of value-added applications of chitin and chitosan is being initiated, investigated, and developed. The widely ranging value-added applications of chitin and chitosan are presented in this review. Chitin and its derivative, chitosan, both highly stable and difficult to degrade materials, can be obtained as 10–20% w/w from the waste seafood shells by suitable chemical processing. One of the significant developments in the new range of applications is the study of the ability of chitosan, as a potentially major environmental treatment material, to remove metal ions from wastewaters. Chitosan is the deac...

Application of Chitosan for the Removal of Metals From Wastewaters by Adsorption—Mechanisms and Models Review

India is bestowed with vast livestock wealth and it is growing at the rate of 6% per annum. The contribution of livestock industry including poultry and fish is increasing substantially in GDP of country which accounts for >40% of total agricultural sector and >12% of GDP. This contribution would have been much greater had the animal by-products been also efficiently utilized. Efficient utilization of by-products has direct impact on the economy and environmental pollution of the country. Non-utilization or under utilization of by-products not only lead to loss of potential revenues but also lead to the added and increasing cost of disposal of these products. Non-utilization of animal by-products in a proper way may create major aesthetic and catastrophic health problems. Besides pollution and hazard aspects, in many cases meat, poultry and fish processing wastes have a potential for recycling raw materials or for conversion into useful products of higher value. Traditions, culture and religion are often important when a meat by-product is being utilized for food. Regulatory requirements are also important because many countries restrict the use of meat by-products for reasons of food safety and quality. By-products such as blood, liver, lung, kidney, brains, spleen and tripe has good nutritive value. Medicinal and pharmaceutical uses of by-product are also highlighted in this review. Waste products from the poultry processing and egg production industries must be efficiently dealt with as the growth of these industries depends largely on waste management. Treated fish waste has found many applications among with which the most important are animal feed, biodiesel/biogas, dietectic products (chitosan), natural pigments (after extraction) and cosmetics (collagen). Available information pertaining to the utilization of by-products and waste materials from meat, poultry and fish and their processing industries has been reviewed here.

Utilization of byproducts and waste materials from meat, poultry and fish processing industries: a review

Characteristics of gelatin from the skins of bigeye snapper, Priacanthus tayenus and Priacanthus macracanthus

Chitosan sponges as sustained release drug carriers

The use of chitosan as a condensing agent to enhance emulsion-mediated gene transfer.

Growth and differentiation of mouse osteoblasts on chitosan-collagen sponges.

Local biodegradable carriers have been studied for use as a skeletal drug delivery system. This study investigated the efficacy of a local biodegradable composite composed of hydroxyapatite, plaster of Paris, and chitosan impregnated with antibiotics to treat methicillin-resistant Staphylococcus aureus. The composite, impregnated with vancomycin, fosfomycin, or sodium fusidate was tested for its sustained elution characteristics during 3 months and compared with similarly impregnated polymethylmethacrylate using the modified disc diffusion technique. Physicochemical properties using scanning electron microscopy and xray diffraction analysis of each preparation also were analyzed. Vancomycin and fosfomycin incorporated into the hydroxyapatite composite inhibited the organism for 3 months, whereas sodium fusidate was effective only for 3 weeks. Vancomycin and fosfomycin loaded into the hydroxyapatite composite had a significantly better inhibitive effect than when loaded in polymethylmethacrylate, whereas sodium fusidate loaded in polymethylmethacrylate showed a significantly better inhibitive effect than when loaded in the hydroxyapatite composite. Scanning electron microscopy and xray diffraction analysis elucidated the patterns of each drug release profile. The local hydroxyapatite composite is a promising local biodegradable delivery system for vancomycin and fosfomycin, whereas PMMA is a better carrier for sodium fusidate in treating methicillin-resistant staphylococcus aureus osteomyelitis.

Kwunchit Oungbho

Papers

Characteristics of gelatin from the skins of bigeye snapper, Priacanthus tayenus and Priacanthus macracanthus

Chitosan sponges as sustained release drug carriers

The use of chitosan as a condensing agent to enhance emulsion-mediated gene transfer.

Growth and differentiation of mouse osteoblasts on chitosan-collagen sponges.

The efficacy of a hydroxyapatite composite as a biodegradable antibiotic delivery system.