K
Kyoung Mi Kim
Researcher at National Institutes of Health
Publications - 35
Citations - 2912
Kyoung Mi Kim is an academic researcher from National Institutes of Health. The author has contributed to research in topics: RNA & RNA-binding protein. The author has an hindex of 19, co-authored 30 publications receiving 2103 citations. Previous affiliations of Kyoung Mi Kim include Korea University & Chungnam National University.
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Journal ArticleDOI
Identification of HuR target circular RNAs uncovers suppression of PABPN1 translation by CircPABPN1.
Kotb Abdelmohsen,Amaresh C. Panda,Rachel Munk,Ioannis Grammatikakis,Dawood B. Dudekula,Supriyo De,Jiyoung Kim,Ji Heon Noh,Kyoung Mi Kim,Jennifer L. Martindale,Myriam Gorospe +10 more
TL;DR: It is proposed that the extensive binding of CircPABPN1 to HuR prevents HuR binding to P ABPN1 mRNA and lowers PABPN1 translation, providing the first example of competition between a circRNA and its cognate mRNA for an RBP that affects translation.
Journal ArticleDOI
RNA in extracellular vesicles
TL;DR: The rising attention to EV‐resident RNAs as biomarkers stems from the fact that RNAs can be detected at extremely low quantities using a number of methods, and this work discusses EV RNAs in cancer and neurodegeneration, two major age‐associated disease processes.
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Cytoplasmic functions of long noncoding RNAs.
TL;DR: The current knowledge of cytoplasmic lncRNAs and the different levels of gene regulation controlled by cytop lncRNA complexes are reviewed, including mRNA turnover, translation, protein stability, sponging of cytosolic factors, and modulation of signaling pathways.
Journal ArticleDOI
Identification of senescence-associated circular RNAs (SAC-RNAs) reveals senescence suppressor CircPVT1.
Amaresh C. Panda,Ioannis Grammatikakis,Kyoung Mi Kim,Supriyo De,Jennifer L. Martindale,Rachel Munk,Xiaoling Yang,Kotb Abdelmohsen,Myriam Gorospe +8 more
TL;DR: Findings indicate that the SAC-RNA CircPVT1, elevated in dividing cells and reduced in senescent cells, sequesters let-7 to enable a proliferative phenotype.
Journal ArticleDOI
Transcriptome signature of cellular senescence.
Gabriel Casella,Rachel Munk,Kyoung Mi Kim,Yulan Piao,Supriyo De,Kotb Abdelmohsen,Myriam Gorospe +6 more
TL;DR: It is proposed that these shared transcriptome profiles will enable the identification of senescent cells in vivo, the investigation of their roles in aging and malignancy and the development of strategies to target senescence cells therapeutically.