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Kyoung Won Seo

Researcher at Seoul National University

Publications -  124
Citations -  1091

Kyoung Won Seo is an academic researcher from Seoul National University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 14, co-authored 103 publications receiving 878 citations. Previous affiliations of Kyoung Won Seo include University of California, Davis & Chungnam National University.

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Histone deacetylase inhibitors decrease proliferation potential and multilineage differentiation capability of human mesenchymal stem cells.

TL;DR: To investigate the role of HDAC in maintenance of self‐renewal and cell proliferation, mesenchymal stem cells that originated from adipose tissue or umbilical cord blood are treated with valproic acid and sodium butyrate.
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SOX2 has a crucial role in the lineage determination and proliferation of mesenchymal stem cells through Dickkopf-1 and c-MYC.

TL;DR: This study shows that SOX2 directly regulates DKK1 expression and, as a consequence, determines the differentiation lineage of hMSCs, a type of ASCs, and regulates proliferation by affecting c-MYC.
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Association of Obesity with Serum Leptin, Adiponectin, and Serotonin and Gut Microflora in Beagle Dogs

TL;DR: Examination of the microbiome revealed that the diversity of the microbial community was lower in the obese group, and microflora enriched with gram‐negative might be related with chronic inflammation status in obese dogs.
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Constrained Optimization Approaches to Estimation of Structural Models: Comment

TL;DR: It is shown that MPEC and NFXP-NK are similar in performance when the sample size is relatively small, however, in problems with larger sample sizes, NFXp-NK outperforms MPEC by a significant margin.
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Anti-tumor effect of adipose tissue derived-mesenchymal stem cells expressing interferon-β and treatment with cisplatin in a xenograft mouse model for canine melanoma.

TL;DR: It is revealed that the combination treatment of cAT-MSC-IFN-β with low-dose cisplatin induced high levels of cell apoptosis, which may prove useful in further explorations of the application of these combined approaches to the treatment of malignant melanoma and other tumors.