K
Kyoungsook Park
Researcher at Sungkyunkwan University
Publications - 27
Citations - 983
Kyoungsook Park is an academic researcher from Sungkyunkwan University. The author has contributed to research in topics: P70-S6 Kinase 1 & Gene expression. The author has an hindex of 16, co-authored 26 publications receiving 922 citations. Previous affiliations of Kyoungsook Park include Samsung.
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Journal Article
Induction of glucose-regulated protein 78 by chronic hypoxia in human gastric tumor cells through a protein kinase C-ε/ERK/AP-1 signaling cascade
TL;DR: This study shows that a PKC-epsilon-Raf-1-MEK-ERK-AP1 signaling cascade acts on a 12-O-tetradecanoylphorbol-13-acetate response element-like element to mediate hypoxia-induced GRP78 expression in human gastric cancer cells.
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Dkk3, downregulated in cervical cancer, functions as a negative regulator of β‐catenin
Eun-Ju Lee,Minwha Jo,Seung Bae Rho,Kyoungsook Park,Yae Na Yoo,Junsoo Park,Myounghee Chae,Wei Zhang,Je Ho Lee +8 more
TL;DR: The finding that Dkk3 is a negative regulator of β‐catenin and its downregulation contribute to an activation of the β‐ catenin signaling pathway is concluded.
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Bcl-2 Promotes Invasion and Lung Metastasis by Inducing Matrix Metalloproteinase-2
Ji-Hyung Choi,Kyusam Choi,Etty N. Benveniste,Young-Sook Hong,Je-Ho Lee,Jhingook Kim,Kyoungsook Park +6 more
TL;DR: It is shown that Bcl-2 promotes tumor invasion and lung metastasis by inducing MMP-2 gene expression through the combined action of transcriptional and posttranslational mechanisms.
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AGR2, a mucinous ovarian cancer marker, promotes cell proliferation and migration.
Kyoungsook Park,Yong Jin Chung,Hyekyung So,Kwang-Soo Kim,Junsoo Park,Mijoung Oh,Minwha Jo,Kyusam Choi,Eun-Ju Lee,Yoon-La Choi,Sang Yong Song,Duk-Soo Bae,Byoung-Gie Kim,Je-Ho Lee +13 more
TL;DR: Human anterior gradient 2 (AGR2) is a potential biomarker for the diagnosis of mucinous ovarian cancer and an ELISA assay may facilitate the early detection of mucineous ovarian cancer using patient serum.
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Activation of stress signaling molecules in bat brain during arousal from hibernation.
TL;DR: The results showed that bat brain undergoes high oxygen demand during arousal from hibernation, and up‐regulation of GRP proteins and activation of JNK, PKCγ and Akt may be critical for neuroprotection and the survival of bats during the repeated process.