L
L. Amanda Sadacca
Researcher at Harvard University
Publications - 1
Citations - 289
L. Amanda Sadacca is an academic researcher from Harvard University. The author has contributed to research in topics: Phosphorylation & Synapse. The author has an hindex of 1, co-authored 1 publications receiving 268 citations.
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Genome-wide activity-dependent MeCP2 phosphorylation regulates nervous system development and function
Sonia Cohen,Harrison W. Gabel,Martin Hemberg,Ashley N. Hutchinson,L. Amanda Sadacca,Daniel H. Ebert,David A. Harmin,Rachel S. Greenberg,Vanessa K. Verdine,Zhaolan Zhou,William C. Wetsel,Anne E. West,Michael E. Greenberg +12 more
TL;DR: It is shown here that disruption of MeCP2 S421 phosphorylation in vivo results in defects in synapse development and behavior, implicating activity-dependent regulation of Me CP2 in brain development and RTT.