L
L. E. Braverman
Researcher at University of Massachusetts Amherst
Publications - 9
Citations - 327
L. E. Braverman is an academic researcher from University of Massachusetts Amherst. The author has contributed to research in topics: Euthyroid & Deiodinase. The author has an hindex of 9, co-authored 9 publications receiving 321 citations.
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Journal ArticleDOI
Selenium deficiency and type II 5'-deiodinase regulation in the euthyroid and hypothyroid rat: evidence of a direct effect of thyroxine
Jean-Pierre Chanoine,Marjorie Safran,A P Farwell,P Tranter,D M Ekenbarger,S Dubord,Sharon Alex,J R Arthur,G J Beckett,L. E. Braverman +9 more
TL;DR: The decrease in brain and pituitary 5'D-II activity in selenium-deficient euthyroid rats is due to the T4-dependent increase in the turnover of the enzyme polypeptide, consistent with the finding that 5' D-II is not a seleno-enzyme.
Journal ArticleDOI
Effects of selenium deficiency on thyroid hormone economy in rats.
Jean-Pierre Chanoine,Marjorie Safran,A P Farwell,S Dubord,Sharon Alex,Scott Stone,J R Arthur,L. E. Braverman,Jack L. Leonard +8 more
TL;DR: It is suggested that increased T3 sulfate generation in selenium-deficient rats may lead to greater T3 availability through enterohepatic recycling of the iodothyronine and may explain why there are only minor changes in serum T3 concentrations in seLenium- deficient rats.
Journal ArticleDOI
Regulation by Thyroid Hormone of the Concentration of Substance P in the Rat Anterior Pituitary
TL;DR: The present study demonstrates that the concentration of iSP in the rat anterior pituitary is affected by the thyroid status of the animal and supports the probability that thyroid hormones participate in the regulation of the synthesis and/or release of i SP from the anterior pituitsary.
Journal ArticleDOI
The effects of gonadal steroids on the content of substance P in the rat anterior pituitary.
TL;DR: The data indicate that AP-SP content is dependent on the gonadal status of the animal and that gonadal steroids interact with thyroid hormones in the regulation of substance P turnover in the AP.
Journal ArticleDOI
The effect of thyroid dysfunction and fasting on placenta inner ring deiodinase activity in the rat.
TL;DR: The results strongly suggest that thyroid status and fasting do not alter P5-Dase activity, and that MMI was not reversed by the administration of supraphysiological doses of T4, Tx, MMI treatment, and fasting all decreased hepatic T4 5'-deiodinase activity in pregnant rats.