L
L. Shackelford
Researcher at Texas A&M University
Publications - 39
Citations - 1013
L. Shackelford is an academic researcher from Texas A&M University. The author has contributed to research in topics: Azoxymethane & Aberrant crypt foci. The author has an hindex of 16, co-authored 39 publications receiving 900 citations. Previous affiliations of L. Shackelford include Alabama Agricultural and Mechanical University.
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Journal ArticleDOI
Bisphosphonates as a supplement to exercise to protect bone during long-duration spaceflight
Adrian LeBlanc,Toshio Matsumoto,Jeffrey A. Jones,Jay R. Shapiro,Thomas Lang,L. Shackelford,Scott M. Smith,H. Evans,E. Spector,Robert Ploutz-Snyder,Jean D. Sibonga,Joyce H. Keyak,Toshitaka Nakamura,Kenjiro Kohri,Hiroshi Ohshima +14 more
TL;DR: The combination of exercise plus an antiresoptive drug may be useful for protecting bone health during long-duration spaceflight.
Journal ArticleDOI
Selected fruits reduce azoxymethane (AOM)-induced aberrant crypt foci (ACF) in Fisher 344 male rats
J. Boateng,Martha Verghese,L. Shackelford,Lloyd T. Walker,J. Khatiwada,S. Ogutu,D.S. Williams,Jeffrey A. Jones,M. Guyton,David Asiamah,F. Henderson,L. Grant,M. DeBruce,Aaron Johnson,S. Washington,C.B. Chawan +15 more
TL;DR: The findings suggest that among the fruits and fruit juices, BLU and POJ contributed to significant (P<0.05) reductions in the formation of AOM-induced ACF.
Journal ArticleDOI
Flax seed oil and flax seed meal reduce the formation of aberrant crypt foci (ACF) in azoxymethane-induced colon cancer in Fisher 344 male rats
TL;DR: Results of this study showed that FSO and FSM reduced the incidence of AOM-induced ACF formation and may therefore be effective chemopreventive agents.
Journal ArticleDOI
Dietary Inulin Suppresses Azoxymethane-Induced Aberrant Crypt Foci and Colon Tumors at the Promotion Stage in Young Fisher 344 Rats
TL;DR: It is indicated that dietary long-chain inulin suppresses AOM-induced ACF formation, an early preneoplastic marker of colon tumorigenesis in rats, and colon tumors, particularly at the promotion stage.
Journal ArticleDOI
Resistive exercise in astronauts on prolonged spaceflights provides partial protection against spaceflight-induced bone loss.
Jean D. Sibonga,Toshio Matsumoto,Jeffrey A. Jones,Jay R Shapiro,Thomas Lang,L. Shackelford,Scott M. Smith,M. Young,Joyce H. Keyak,Kenjiro Kohri,Hiroshi Ohshima,E. Spector,Adrian LeBlanc +12 more
TL;DR: It is concluded that a bisphosphonate, when combined with resistive exercise, enhances the preservation of bone mass because of the added suppression of bone resorption in trabecular bone compartment not evident with ARED alone.