L
Laily B. Din
Researcher at National University of Malaysia
Publications - 105
Citations - 1411
Laily B. Din is an academic researcher from National University of Malaysia. The author has contributed to research in topics: Apoptosis & DPPH. The author has an hindex of 19, co-authored 105 publications receiving 1283 citations. Previous affiliations of Laily B. Din include Murdoch University & Hoshi University.
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Journal ArticleDOI
Synthesis of silver nanoparticles with antibacterial activity using the lichen Parmotrema praesorediosum.
Ropisah Mie,Mohd Wahid Samsudin,Laily B. Din,Azizan Ahmad,Nazlina Ibrahim,Siti Noor Adnalizawati Adnan +5 more
TL;DR: The synthesis of silver nanoparticles from the reduction of silver nitrate and an aqueous extract of the lichen Parmotrema praesorediosum as a reductant as well as a stabilizer reveals potential antibacterial activity against Gram-negative bacteria.
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Loss of mitochondrial transmembrane potential and caspase-9 activation during apoptosis induced by the novel styryl-lactone goniothalamin in HL-60 leukemia cells
TL;DR: The results demonstrate that goniothalamin-induced apoptosis occurs via the mitochondrial pathway in a caspase dependent manner.
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Caspases‐3 and ‐7 are activated in goniothalamin‐induced apoptosis in human Jurkat T‐cells
Salmaan H. Inayat-Hussain,Annuar Bin Osman,Laily B. Din,Abdul M. Ali,Roger T. Snowden,Marion MacFarlane,Kelvin Cain +6 more
TL;DR: It is demonstrated that activation of at least two effector caspases is a key feature of goniothalamin‐induced apoptosis in Jurkat T‐cells and pre‐treatment with the caspase inhibitor benzyloxycarbonyl‐Val‐Ala‐Asp fluoromethyl ketone blocked apoptosis and the resultant cleavage of these caspased and PARP.
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Cytotoxic properties of oligostilbenoids from the tree barks of Hopea dryobalanoides.
Sahidin,Euis H. Hakim,Lia D. Juliawaty,Yana M. Syah,Laily B. Din,Emilio L. Ghisalberti,Jalifah Latip,Ikram M. Said,Sjamsul Arifin Achmad +8 more
TL;DR: A new modified stilbene dimer, diptoindonesin D, was isolated from the acetone extract of the tree bark of Hopea dryobalanoides and found to be the most active with IC50 of 5.7 μm.
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Goniothalamin induces apoptosis in vascular smooth muscle cells.
Kok Meng Chan,Nor Fadilah Rajab,M.H.A. Ishak,Abdul M. Ali,K. Yusoff,Laily B. Din,Salmaan H. Inayat-Hussain +6 more
TL;DR: The data show that GN initially induces DNA damage which subsequently leads to cytotoxicity primarily via apoptosis in VSMCs, and GN effects were comparable to rapamycin.