L
Lana S. Rothenburg
Researcher at Sunnybrook Health Sciences Centre
Publications - 12
Citations - 1498
Lana S. Rothenburg is an academic researcher from Sunnybrook Health Sciences Centre. The author has contributed to research in topics: Apathy & Alzheimer's disease. The author has an hindex of 11, co-authored 12 publications receiving 1307 citations. Previous affiliations of Lana S. Rothenburg include University of Toronto.
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Journal ArticleDOI
A Meta-Analysis of Cytokines in Alzheimer's Disease
Walter Swardfager,Krista L. Lanctôt,Krista L. Lanctôt,Lana S. Rothenburg,Amy P. Wong,Amy P. Wong,Jaclyn Cappell,Nathan Herrmann,Nathan Herrmann +8 more
TL;DR: The results strengthen the clinical evidence that AD is accompanied by an inflammatory response, particularly higher peripheral concentrations of IL-6, TNF-α, IL-1β, TGF-β,IL-12 and IL-18 and higher CSF concentrations of T GF-β.
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Methylphenidate for the Treatment of Apathy in Alzheimer Disease: Prediction of Response Using Dextroamphetamine Challenge
Nathan Herrmann,Lana S. Rothenburg,Sandra E. Black,Michelle Ryan,Barbara A. Liu,Usoa E. Busto,Krista L. Lanctôt +6 more
TL;DR: A randomized, double-blind, placebo-controlled crossover trial of methylphenidate in a sample of 13 apathetic AD patients, finding that psychostimulants may be effective in treating features of apathy in AD, and dopaminergic changes may predict response.
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A SPECT study of apathy in Alzheimer's disease
Krista L. Lanctôt,Shehnaz Moosa,Nathan Herrmann,Farrell S. Leibovitch,Lana S. Rothenburg,Adolfo Cotter,Sandra E. Black +6 more
TL;DR: In this group of nondepressed outpatients meeting criteria for probable AD, apathetic subjects displayed significant perfusion differences compared to nonapathetic subjects.
Journal ArticleDOI
The Relationship Between Inflammatory Markers and Post Stroke Cognitive Impairment
Lana S. Rothenburg,Nathan Herrmann,Walter Swardfager,Sandra E. Black,Gayla Tennen,Alexander Kiss,David J. Gladstone,Jon Erik Ween,Abraham Snaiderman,Krista L. Lanctôt +9 more
TL;DR: A post stroke inflammatory response may be important in subacute, PSCI, and backward stepwise elimination linear regression showed that higher concentrations of serum CRP predicted lower post stroke global cognition.
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A placebo-controlled trial of valproate for agitation and aggression in Alzheimer's disease.
TL;DR: Valproate is not effective for the management of agitation in moderate-to-severe AD, and may be poorly tolerated in this population of institutionalized AD patients.