L
Larissa S. Bernardi
Researcher at Universidade Federal de Santa Catarina
Publications - 37
Citations - 363
Larissa S. Bernardi is an academic researcher from Universidade Federal de Santa Catarina. The author has contributed to research in topics: Differential scanning calorimetry & Dissolution. The author has an hindex of 11, co-authored 33 publications receiving 286 citations.
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Journal ArticleDOI
Characterization of venlafaxine hydrochloride and compatibility studies with pharmaceutical excipients
Larissa S. Bernardi,Paulo R. Oliveira,Fábio S. Murakami,Marcos Antonio Segatto Silva,Silvia H. M. Borgmann,Simone Gonçalves Cardoso +5 more
TL;DR: The thermal analytical study of venlafaxine hydrochloride, a third generation antidepressant, was investigated using thermogravimetry (TG) and differential scanning calorimetry(DSC) as mentioned in this paper.
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Thermal characterization and compatibility studies of norfloxacin for development of extended release tablets
Paulo R. Oliveira,Larissa S. Bernardi,Fábio S. Murakami,Cassiana Mendes,Marcos Antonio Segatto Silva +4 more
TL;DR: In this article, the thermal behavior of NFX was investigated using TG and DSC techniques, and compatibility studies between NFX and pharmaceutical excipients, including three hydrophilic polymers were carried out in order to develop a new formulation of N FX to obtain extended release tablets with an approved quality.
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Solid-State Characterization of Different Crystalline Forms of Sitagliptin
Nayana C. F. Stofella,Andressa Veiga,Laiane J. Oliveira,Elisa De Freitas Montin,Itamar Francisco Andreazza,Marco Aurélio da Silva Carvalho Filho,Larissa S. Bernardi,Paulo R. Oliveira,Fábio S. Murakami +8 more
TL;DR: Through this study, it was possible to establish the most suitable crystalline form of sitagliptin for the development of a safe, effective and appropriate pharmaceutical dosage form.
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Formulation Development and Stability Studies of Norfloxacin Extended-Release Matrix Tablets
Paulo R. Oliveira,Cassiana Mendes,Lilian Klein,Maximiliano da Silva Sangoi,Larissa S. Bernardi,Marcos Antonio Segatto Silva +5 more
TL;DR: A new hydrophilic matrix system containing norfloxacin (NFX) demonstrated a combination of extended and complete in vitro drug release, which could provide an increased bioavailability in vivo.
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Fluconazole–excipient compatibility studies as the first step in the development of a formulation candidate for biowaiver
Lilian Klein Teleginski,Aline Biggi Maciel,Cassiana Mendes,Marcos Antonio Segatto Silva,Larissa S. Bernardi,Paulo R. Oliveira +5 more
TL;DR: The composition of a commercially available fluconazole formulation in the form of capsules was qualitatively determine with regard to the presence of critical excipients and to carry out compatibility studies by differential scanning calorimetry (DSC).