Larry G. Moss

TL;DR: The crystal structure of recombinant wild-type green fluorescent protein (GFP) has been solved to a resolution of 1.9 Å by multiwavelength anomalous dispersion phasing methods and the identification of the dimer contacts may allow mutagenic control of the state of assembly of the protein.

TL;DR: Cloning of the human mafA (hMafA) is reported and it is demonstrated that it can specifically bind the insulin enhancer element RIPE3b and activate insulin-gene expression, suggesting that mMafA has an essential role in the function and differentiation of β-cells and thus may be associated with the pathophysiological origins of diabetes.

TL;DR: These results provide the first evidence of how perilipin functions and suggest that TNF-α regulates lipolysis, in part, by decreasing perilipIn protein levels at the lipid droplet surface.

TL;DR: Experiments showing a reduction in the response to glucose in the presence of the calcium channel blocker verapamil suggest that calcium plays a role in the glucose response, possibly via regulation of factors interacting with this limited portion of the insulin gene.

TL;DR: In this article, the functions of isolated portions of the insulin, IAPP, and beta GK promoters were studied by using transient expression and DNA binding assays, showing that the patterns of expression of the beta-cell-specific genes result in part from sharing the same transcriptional regulators.