L
Larry Sirls
Researcher at Beaumont Hospital
Publications - 95
Citations - 3335
Larry Sirls is an academic researcher from Beaumont Hospital. The author has contributed to research in topics: Urinary incontinence & Stress incontinence. The author has an hindex of 27, co-authored 86 publications receiving 3022 citations. Previous affiliations of Larry Sirls include National Institutes of Health & University of Texas Southwestern Medical Center.
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Journal ArticleDOI
Retropubic versus Transobturator Midurethral Slings for Stress Incontinence
Holly E. Richter,Michael E. Albo,Halina M. Zyczynski,Kimberly Kenton,Peggy Norton,Larry Sirls,Stephen R. Kraus,Toby C. Chai,Gary E. Lemack,Kimberly J. Dandreo,R. Edward Varner,Shawn A. Menefee,Chiara Ghetti,Linda Brubaker,Ingrid Nygaard,Salil Khandwala,Thomas A. Rozanski,Harry W. Johnson,Joseph I. Schaffer,Anne M. Stoddard,Robert L. Holley,Charles W. Nager,Pamela A. Moalli,Elizabeth R. Mueller,Amy Arisco,Marlene M. Corton,Sharon L. Tennstedt,T. Debuene Chang,E. Ann Gormley,Heather J. Litman +29 more
TL;DR: The 12-month rates of objectively assessed success of treatment for stress incontinence with the retropubic and transobturator approaches met the prespecified criteria for equivalence; the rates of subjectively assessed success were similar between groups but did not meet the criteria for interchange.
Journal ArticleDOI
Burch Colposuspension versus Fascial Sling to Reduce Urinary Stress Incontinence
Michael E. Albo,Holly E. Richter,Linda Brubaker,Peggy Norton,Stephen R. Kraus,Philippe E. Zimmern,Toby C. Chai,Halina M. Zyczynski,Ananias C. Diokno,Sharon L. Tennstedt,Charles W. Nager,L. Keith Lloyd,MaryPat FitzGerald,Gary E. Lemack,Harry W. Johnson,Wendy W. Leng,Veronica T. Mallett,Anne M. Stoddard,Shawn A. Menefee,R. Edward Varner,Kimberly Kenton,Pamela A. Moalli,Larry Sirls,Kimberly J. Dandreo,John W. Kusek,Leroy M. Nyberg,William D. Steers +26 more
TL;DR: A multicenter, randomized clinical trial comparing two procedures--the pubovaginal sling, using autologous rectus fascia, and the Burch colposuspension--among women with stress incontinence results in a higher rate of successful treatment of stressincontinence but also greater morbidity than the Burches.
Journal ArticleDOI
A new injectable bulking agent for treatment of stress urinary incontinence: results of a multicenter, randomized, controlled, double-blind study of Durasphere
Deborah J. Lightner,Carlos Calvosa,Roger Andersen,Ira W. Klimberg,C.Gilberto Brito,Jeffrey Snyder,Donald F. Gleason,David Killion,James Macdonald,A.U Khan,Ananias C. Diokno,Larry Sirls,Daniel Saltzstein +12 more
TL;DR: The product design and initial clinical data suggest the potential for greater durability of the clinical benefit, with the possibility of a permanent solution for SUI due to ISD in some patients.
Journal ArticleDOI
Adverse events over two years after retropubic or transobturator midurethral sling surgery: findings from the Trial of Midurethral Slings (TOMUS) study
Linda Brubaker,Peggy Norton,Michael E. Albo,Toby C. Chai,Kimberly J. Dandreo,Keith Lloyd,Jerry L. Lowder,Larry Sirls,Gary E. Lemack,Amy Arisco,Yan Xu,John W. Kusek +11 more
TL;DR: Adverse events vary by procedure, but are common after midurethral sling, and most events resolve without significant sequelae.
Journal ArticleDOI
Urodynamic Measures Do Not Predict Stress Continence Outcomes After Surgery for Stress Urinary Incontinence in Selected Women
Charles W. Nager,Charles W. Nager,MaryPat FitzGerald,MaryPat FitzGerald,Stephen R. Kraus,Toby C. Chai,Toby C. Chai,Halina M. Zyczynski,Halina M. Zyczynski,Larry Sirls,Larry Sirls,Gary E. Lemack,L. Keith Lloyd,L. Keith Lloyd,Heather J. Litman,Anne M. Stoddard,Jan Baker,Jan Baker,William D. Steers,William D. Steers +19 more
TL;DR: A nearly statistically significant trend is found that women with urodynamic stress incontinence are twice as likely to have a successful overall outcome from surgical management of stress urinary incontinent as women without urod dynamic stressincontinence.