L
Larry W. Oberley
Researcher at University of Iowa
Publications - 229
Citations - 24150
Larry W. Oberley is an academic researcher from University of Iowa. The author has contributed to research in topics: Superoxide dismutase & Superoxide. The author has an hindex of 82, co-authored 229 publications receiving 23354 citations. Previous affiliations of Larry W. Oberley include Roy J. and Lucille A. Carver College of Medicine & Wabash College.
Papers
More filters
Journal ArticleDOI
Free radicals and diabetes
TL;DR: Not only are oxygen radicals involved in the cause of diabetes, they also appear to play a role in some of the complications seen in long-term treatment of diabetes.
Journal Article
Role of Superoxide dismutase in cancer: a review.
TL;DR: It is shown how diminished enzyme activities along with radical production may lead to many of the observed properties of cancer cells.
Journal ArticleDOI
Manganous superoxide dismutase is essential for cellular resistance to cytotoxicity of tumor necrosis factor
TL;DR: Overexpression of MnSOD confers increased resistance to TNF plus cycloheximide on the 293 human embryonic kidney cell line and implicate mitochondrially generated O2- as a key component of TNF-mediated tumor cell killing.
Journal ArticleDOI
Redox regulation of transcriptional activators
Yi Sun,Larry W. Oberley +1 more
TL;DR: Differential regulation of these transcriptional activators, which in turn, regulate many target/effector genes, may provide an additional mechanism by which small antioxidant molecules play protective roles in anticancer and antiaging processes.
Journal ArticleDOI
An assay for superoxide dismutase activity in mammalian tissue homogenates.
TL;DR: The inclusion of BCS in the NBT assay system was shown to make the accurate measurement of SOD activity in tissues with interferences possible, and the most effective compounds were metal chelators that were also electron transport chain inhibitors.