L
Lars M. Blank
Researcher at RWTH Aachen University
Publications - 355
Citations - 10606
Lars M. Blank is an academic researcher from RWTH Aachen University. The author has contributed to research in topics: Chemistry & Pseudomonas putida. The author has an hindex of 49, co-authored 301 publications receiving 8011 citations. Previous affiliations of Lars M. Blank include University of Marburg & Technical University of Dortmund.
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Journal ArticleDOI
Integration of Genetic and Process Engineering for Optimized Rhamnolipid Production Using Pseudomonas putida.
Till Tiso,Till Tiso,Nina Ihling,Nina Ihling,Sonja Kubicki,Sonja Kubicki,Andreas Biselli,Andreas Biselli,Andreas Schonhoff,Isabel Bator,Isabel Bator,Stephan Thies,Stephan Thies,Tobias Karmainski,Tobias Karmainski,Sebastian Kruth,Sebastian Kruth,Anna-Lena Willenbrink,Anna-Lena Willenbrink,Anita Loeschcke,Anita Loeschcke,Petra Zapp,Andreas Jupke,Andreas Jupke,Karl-Erich Jaeger,Karl-Erich Jaeger,Jochen Büchs,Jochen Büchs,Lars M. Blank,Lars M. Blank +29 more
TL;DR: expression cassettes for stable integration of the rhamnolipid biosynthesis genes into the genome outperformed plasmid-based expression systems and underlines the need for multidisciplinary approaches to address the challenges associated with achieving sustainable production of microbial secondary metabolites.
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From beech wood to itaconic acid: case study on biorefinery process integration.
Lars Regestein,Lars Regestein,Tobias Klement,Philipp M. Grande,Philipp M. Grande,Dirk Kreyenschulte,Benedikt Heyman,Tim Maßmann,Armin Eggert,Robert Sengpiel,Yumei Wang,Nick Wierckx,Lars M. Blank,Antje C. Spiess,Antje C. Spiess,Walter Leitner,Walter Leitner,Carsten Bolm,Matthias Wessling,Andreas Jupke,Miriam A. Rosenbaum,Miriam A. Rosenbaum,Jochen Büchs +22 more
TL;DR: The presented comprehensive examination and discussion of the itaconate synthesis process—as a case study—demonstrates the impact of realistic process conditions on product yield, choice of whole cell catalyst, chemocatalysts and organic solvent system, operation mode, and, finally, the selection of a downstream concept.
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Corrigendum: Multi-Omics Analysis of Fatty Alcohol Production in Engineered Yeasts Saccharomyces cerevisiae and Yarrowia lipolytica (Front Genet, (2019), 10, (747), 10.3389/fgene.2019.00747)
Jonathan Dahlin,Carina Holkenbrink,Eko Roy Marella,Guokun Wang,Ulf W. Liebal,Christian Lieven,D. Weber,Douglas McCloskey,Hong-Lei Wang,Birgitta E. Ebert,Markus J. Herrgård,Lars M. Blank,Irina Borodina +12 more
TL;DR: Hong-Lei Wang was not included as an author in the published article as discussed by the authors, and the corrected Author Contributions Statement appears below the corrected author contribution statement: Corrected Author Contributions statement
Journal ArticleDOI
Strain- and Substrate-Dependent Redox Mediator and Electricity Production by Pseudomonas aeruginosa
TL;DR: A comparison of the phenazine-dependent electroactivities of three Pseudomonas strains is presented, finding significant differences in substrate-dependent phenazine production and resulting anodic current generation for the three strains.
Journal ArticleDOI
Metabolic engineering of Ustilago trichophora TZ1 for improved malic acid production
Thiemo Zambanini,Hamed Hosseinpour Tehrani,Elena Geiser,Christiane K. Sonntag,Joerg M. Buescher,Guido Meurer,Nick Wierckx,Lars M. Blank +7 more
TL;DR: Investigation and adaptation of existing molecular tools from U. maydis for use in U. trichophora open up a wide range of possibilities for further optimization, especially combinatorial metabolic engineering to increase the flux from pyruvate to malic acid and to reduce by-product formation.