L
Laura Butruille
Researcher at university of lille
Publications - 38
Citations - 646
Laura Butruille is an academic researcher from university of lille. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 12, co-authored 27 publications receiving 338 citations. Previous affiliations of Laura Butruille include Lille University of Science and Technology.
Papers
More filters
Journal ArticleDOI
PPAR control of metabolism and cardiovascular functions
TL;DR: Peroxisome proliferator-activated receptor-α (PPARα), PPARδ and PPARγ are transcription factors that regulate gene expression following ligand activation as discussed by the authors.
Journal ArticleDOI
Maternal high-fat diet during suckling programs visceral adiposity and epigenetic regulation of adipose tissue stearoyl-CoA desaturase-1 in offspring.
Laura Butruille,Lucie Marousez,Charlène Pourpe,Frédérik Oger,Simon Lecoutre,Daniel Catheline,Solvig Görs,Cornelia C. Metges,Céline Guinez,Christine Laborie,Philippe Deruelle,Jérôme Eeckhoute,Christophe Breton,Philippe Legrand,Jean Lesage,Delphine Eberlé +15 more
TL;DR: The data reveal that maternal HF feeding during suckling programs long-term eWAT expansion in part by SCD1 epigenetic reprogramming occurred with drastic changes in breast milk FA composition, suggesting that dietary FAs are key metabolic programming factors in the early postnatal period.
Journal ArticleDOI
The nuclear receptor FXR inhibits Glucagon-Like Peptide-1 secretion in response to microbiota-derived Short-Chain Fatty Acids
Sarah Ducastel,Véronique Touche,Mohamed-Sami Trabelsi,Alexis Boulinguiez,Laura Butruille,Margaux Nawrot,Simon Peschard,Oscar Chávez-Talavera,Emilie Dorchies,Emmanuelle Vallez,Jean-Sébastien Annicotte,Steve Lancel,Olivier Briand,Kadiombo Bantubungi,Sandrine Caron,Laure B. Bindels,Nathalie M. Delzenne,Anne Tailleux,Bart Staels,Sophie Lestavel +19 more
TL;DR: It is demonstrated that FXR activation decreases L-cell GLP-1 secretion in response to inulin-derived SCFA by reducing FFAR2 expression and signaling, mainly by decreasing FFAR1 expression and downstream Gαq-signaling.
Journal ArticleDOI
Apelin controls fetal and neonatal glucose homeostasis and is altered by maternal undernutrition
Sylvain Mayeur,Jean-Sébastien Wattez,Marie-Amélie Lukaszewski,Simon Lecoutre,Laura Butruille,Anne Drougard,Delphine Eberlé,Bruno Bastide,Christine Laborie,Laurent Storme,Claude Knauf,Didier Vieau,Christophe Breton,Jean Lesage +13 more
TL;DR: It is demonstrated that apelin controls fetal and neonatal glucose homeostasis and is altered by fetal growth restriction induced by maternal undernutrition.
Journal ArticleDOI
Maternal obesity programs increased leptin gene expression in rat male offspring via epigenetic modifications in a depot-specific manner.
Simon Lecoutre,Frédérik Oger,Charlène Pourpe,Laura Butruille,Lucie Marousez,Anne Dickes-Coopman,Christine Laborie,Céline Guinez,Jean Lesage,Didier Vieau,Claudine Junien,Delphine Eberlé,Anne Gabory,Jérôme Eeckhoute,Christophe Breton +14 more
TL;DR: In this article, two potential enhancers located upstream and downstream of the leptin transcription start site exhibited strong dynamic epigenomic remodeling during adipocyte differentiation, consistent with the DOHaD hypothesis.