C
Christophe Breton
Researcher at university of lille
Publications - 65
Citations - 4020
Christophe Breton is an academic researcher from university of lille. The author has contributed to research in topics: Offspring & Adipose tissue. The author has an hindex of 31, co-authored 65 publications receiving 3742 citations. Previous affiliations of Christophe Breton include Lille University of Science and Technology & McGill University.
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Journal ArticleDOI
Maternal stress alters endocrine function of the feto-placental unit in rats
Jérôme Mairesse,Jean Lesage,Christophe Breton,Bernadette Breant,Tom Hahn,Muriel Darnaudéry,Suzanne L. Dickson,Jonathan R. Seckl,B. Blondeau,Didier Vieau,Stefania Maccari,Odile Viltart +11 more
TL;DR: Data emphasize the impact of PS on both fetal growth and endocrine function as well as on placental physiology, suggesting that PS could program processes implied in adult biology and pathophysiology.
Journal ArticleDOI
Time-resolved FRET between GPCR ligands reveals oligomers in native tissues
Laura Albizu,Martin Cottet,Martin Cottet,Martin Cottet,Michaela Kralikova,Stoytcho Stoev,René Seyer,René Seyer,René Seyer,Isabelle Brabet,Isabelle Brabet,Isabelle Brabet,Thomas Roux,Herve Bazin,Emmanuel Bourrier,Laurent Lamarque,Christophe Breton,Marie-Laure Rives,Amy Hauck Newman,Jonathan A. Javitch,Eric Trinquet,Maurice Manning,Jean-Philippe Pin,Jean-Philippe Pin,Jean-Philippe Pin,Bernard Mouillac,Bernard Mouillac,Bernard Mouillac,Thierry Durroux,Thierry Durroux,Thierry Durroux +30 more
TL;DR: A time-resolved FRET strategy based on receptor labeling with selective fluorescent ligands was developed and applied to native tissues and succeeded in demonstrating the presence of oxytocin receptor dimers and/or oligomers in mammary gland.
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Maternal perinatal undernutrition drastically reduces postnatal leptin surge and affects the development of arcuate nucleus proopiomelanocortin neurons in neonatal male rat pups.
Fabien Delahaye,Christophe Breton,Pierre Yves Risold,Mihaela Enache,Isabelle Dutriez-Casteloot,Christine Laborie,Jean Lesage,Didier Vieau +7 more
TL;DR: The data showed that maternal undernutrition drastically reduces the postnatal surge of plasma leptin, disturbing particularly the hypothalamic wiring as well as the gene expression of the anorexigenic POMC neurons in male rat pups, which might contribute to the adult metabolic disorders resulting from perinatal growth retardation.
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Sex- and diet-specific changes of imprinted gene expression and DNA methylation in mouse placenta under a high-fat diet.
Catherine Gallou-Kabani,Anne Gabory,Anne Gabory,Jörg Tost,Mohsen Karimi,Sylvain Mayeur,Jean Lesage,Elsa Boudadi,Marie Sylvie Gross,Julien Taurelle,Alexandre Vigé,Christophe Breton,Brigitte Reusens,Claude Remacle,Didier Vieau,Tomas J. Ekström,Jean-Philippe Jais,Claudine Junien,Claudine Junien +18 more
TL;DR: A HFD during gestation triggers sex-specific epigenetic alterations within CpG and throughout the genome, together with the deregulation of clusters of imprinted genes important in the control of many cellular, metabolic and physiological functions potentially involved in adaptation and/or evolution.
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Cell-Surface Estrogen Receptors Mediate Calcium-Dependent Nitric Oxide Release in Human Endothelia
George B. Stefano,Vincent Prevot,Jean-Claude Beauvillain,Patrick Cadet,Caterina Fimiani,Ingeborg Welters,Gregory L. Fricchione,Christophe Breton,Philippe Lassalle,Michel Salzet,Thomas V. Bilfinger +10 more
TL;DR: It was shown with the use of dual emission microfluorometry that 17beta-estradiol-stimulated release of endothelial NO was dependent on the initial stimulation of intracellular calcium transients.