L
Laura Gorrell
Researcher at National Institutes of Health
Publications - 3
Citations - 25
Laura Gorrell is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Procollagen peptidase & Medicine. The author has an hindex of 1, co-authored 1 publications receiving 10 citations.
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Journal ArticleDOI
Mechanisms of procollagen and HSP47 sorting during ER-to-Golgi trafficking
Shakib Omari,Elena Makareeva,Laura Gorrell,Michal Jarnik,Jennifer Lippincott-Schwartz,Sergey Leikin +5 more
TL;DR: It is suggested that procollagen and HSP47 sorting occurs at ERES beforeprocollagen is exported from the ER in Golgi-bound transport intermediates, providing new insights into mechanisms of Procollagen trafficking.
Journal ArticleDOI
ER, Mitochondria, and ISR Regulation by mt‐HSP70 and ATF5 upon Procollagen Misfolding in Osteoblasts
TL;DR: The present study of a G610C mouse model of OI by multiple transcriptomic techniques provides first solid clues to how OBs respond to misfolded procollagen accumulation in the endoplasmic reticulum (ER) and how this response affects OB function.
Posted ContentDOI
The periaqueductal grey in chronic low back pain: dysregulated metabolites and function
Laura Sirucek,I. De Schoenmacker,Laura Gorrell,Robin Luetolf,Anke Langenfeld,Mirjam Baechler,Brigitte Wirth,Michèle Hubli,Niklaus Zoelch,Petra Schweinhardt +9 more
TL;DR: In this paper , a cross-sectional magnetic resonance spectroscopy (MRS) study investigated whether a lower excitatory/inhibitory tone is also observed in the periaqueductal grey (PAG) of patients with non-specific chronic low back pain (CLBP) and whether this would relate to altered psychophysical measures of descending pain modulation and experimental pressure pain sensitivity.