L
Laura Pop
Researcher at Iuliu Hațieganu University of Medicine and Pharmacy
Publications - 46
Citations - 673
Laura Pop is an academic researcher from Iuliu Hațieganu University of Medicine and Pharmacy. The author has contributed to research in topics: Cancer & Breast cancer. The author has an hindex of 14, co-authored 38 publications receiving 448 citations.
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Journal ArticleDOI
The Epigenetics of Triple-Negative and Basal-Like Breast Cancer: Current Knowledge
TL;DR: This review aims to synthesize the epigenetic discoveries that have been made related to the triple-negative breast cancer, which is resistant to both endocrine and targeted therapies, leading to its poor prognosis.
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miRNA expression profiling in formalin-fixed paraffin-embedded endometriosis and ovarian cancer samples.
Ovidiu-Leonard Braicu,Liviuta Budisan,Rares Buiga,Ancuta Jurj,Patriciu Achimas-Cadariu,Laura Pop,Cornelia Braicu,Alexandru Irimie,Ioana Berindan-Neagoe +8 more
TL;DR: Several deregulated pathways due to abnormal miRNA expression in endometriosis and ovarian cancer, which in turn is responsible for pathogenesis are revealed; this differential expression of miRNAs can be exploited as a therapeutic target.
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How to Diagnose and Treat a Cancer of Unknown Primary Site.
Ciprian Tomuleasa,Florin Zaharie,Mihai-Stefan Muresan,Laura Pop,Zsolt Fekete,Delia Dima,Ioana Frinc,Adrian P. Trifa,Cristian Berce,Ancuta Jurj,Ioana Berindan-Neagoe,Mihnea Zdrenghea +11 more
TL;DR: Both the diagnostic challenges for patients with a cancer of unknown primary site as well as the current available therapeutic options are summarized, with emphasis on the management of this unique disease entity.
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Aberrant miRNAs expressed in HER-2 negative breast cancers patient.
Cornelia Braicu,Lajos Raduly,Gabriela Morar-Bolba,Roxana Cojocneanu,Ancuta Jurj,Laura Pop,Valentina Pileczki,Cristina Ciocan,Alin Moldovan,Alexandru Irimie,Alexandru Eniu,Patriciu Achimas-Cadariu,Angelo Paradiso,Ioana Berindan-Neagoe +13 more
TL;DR: The miR-200b presents a great potential for the future advancements in the diagnostic/prognostic and therapeutic approach of TNBC, however, this needs to be further integrated in a regulatory network that acts in conjunction with other markers that affect the patients’ prognosis or response to therapy.
Journal ArticleDOI
Gene expression profiling reveals activation of the FA/BRCA pathway in advanced squamous cervical cancer with intrinsic resistance and therapy failure
Ovidiu Balacescu,Loredana Balacescu,Oana Tudoran,Nicolae Todor,Meda Rus,Rares Buiga,Sergiu Susman,Bogdan Fetica,Laura Pop,Laura Iuliana Maja,Simona Visan,Claudia Ordeanu,Ioana Berindan-Neagoe,Viorica Nagy +13 more
TL;DR: The findings suggest that FA/BRCA pathway plays an important role in treatment failure in advanced cervical cancer and the assessment of FANCD2, RAD51, BRCA1 and BRIP1 nuclear proteins could provide important information about the patients at risk for treatment failure.