L
Laura Uelze
Researcher at Federal Institute for Risk Assessment
Publications - 15
Citations - 180
Laura Uelze is an academic researcher from Federal Institute for Risk Assessment. The author has contributed to research in topics: Salmonella enterica & Illumina dye sequencing. The author has an hindex of 4, co-authored 13 publications receiving 82 citations.
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Journal ArticleDOI
Typing methods based on whole genome sequencing data
Laura Uelze,Josephine Grützke,Maria Borowiak,Jens A. Hammerl,Katharina Juraschek,Carlus Deneke,Simon H. Tausch,Burkhard Malorny +7 more
TL;DR: The relevant approaches for phylogenomic studies for outbreak studies are described and an overview of selected tools for the characterization of foodborne pathogens based on WGS data are given.
Journal ArticleDOI
Performance and Accuracy of Four Open-Source Tools for In Silico Serotyping of Salmonella spp. Based on Whole-Genome Short-Read Sequencing Data.
Laura Uelze,Maria Borowiak,Carlus Deneke,Istvan Szabo,Jennie Fischer,Simon H. Tausch,Burkhard Malorny +6 more
TL;DR: Although the accuracy of computational serovar predictions is still not quite on par with traditional serotyping by Salmonella reference laboratories, the command-line tools investigated in this study perform a rapid, efficient, inexpensive, and reproducible analysis, which can be integrated into in-house characterization pipelines.
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Decentralized Investigation of Bacterial Outbreaks Based on Hashed cgMLST
TL;DR: ChewieSnake as discussed by the authors is a simple and simple-to-use cgMLST workflow that combines the concept of allele hashing with the chewBBACA algorithm for the analysis of whole-genome sequencing.
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German-Wide Interlaboratory Study Compares Consistency, Accuracy and Reproducibility of Whole-Genome Short Read Sequencing.
Laura Uelze,Maria Borowiak,Markus Bönn,Erik Brinks,Carlus Deneke,Thomas Hankeln,Sylvia Kleta,Larissa Murr,Kerstin Stingl,Kathrin Szabo,Simon H. Tausch,Anne Wöhlke,Burkhard Malorny +12 more
TL;DR: Investigation of next-generation short read sequencing between ten laboratories involved in food safety from Germany and Austria found Illumina short read data to be more accurate and consistent and consistent than Ion Torrent sequence data, with little variation between the different Illumina instruments.
Journal ArticleDOI
Toward an Integrated Genome-Based Surveillance of Salmonella enterica in Germany.
Laura Uelze,Natalie Becker,Maria Borowiak,Ulrich Busch,Alexandra Dangel,Carlus Deneke,Jennie Fischer,Antje Flieger,Sabrina Hepner,Ingrid Huber,Ulrich Methner,Jörg Linde,Michael Pietsch,Sandra Simon,Andreas Sing,Simon H. Tausch,Istvan Szabo,Burkhard Malorny +17 more
TL;DR: In this article, the authors present a working solution for cross-sector interpretation of sequencing data from different sources (such as human, veterinarian, food, feed and environmental) and outline how a decentralised data analysis can contribute to a uniform cluster detection and facilitate outbreak investigations.