Lauren C. Burcea

TL;DR: The WUCaMP assay is a robust and sensitive method to detect somatic variants of clinical significance in molecular oncology laboratories, with reduced time and cost of genetic analysis allowing for strategic patient management.

TL;DR: Rapid and extraction-free detection of SARS-CoV-2 from saliva by colorimetric RT-LAMP is a simple, sensitive, and cost-effective approach with broad potential to expand diagnostic testing for the virus causing COVID-19.

TL;DR: Preliminary results demonstrate a promising approach to overcome the current bottlenecks limiting widespread testing of rapid colorimetric assays using reverse-transcription loop-mediated isothermal amplification optimized on human saliva samples without an RNA purification step.

TL;DR: MVRSION represents a generally applicable tool for taxonomic classification that is superior to single-region 16S rRNA methods, resource efficient, highly scalable for assessing the microbial composition of up to thousands of samples concurrently, with multiple applications ranging from whole community profiling to targeted tracking of organisms of interest in diverse habitats as a function of specified variables/perturbations.

TL;DR: Results suggest that phosphorylation of specific residues of PLM may direct PLM from an intracellular compartment to the plasma membrane.