Lauren P Westhaver

TL;DR: Findings indicate that modulating the stress response can be used to exploit the hypoxic niche of GBM tumors, causing cell death by disrupting pro-survival stress responses and control of protein synthesis.

TL;DR: In this article , the authors describe the lymphocyte response to mitoDAMPs and demonstrate that natural killer (NK) cells and T cells adopt regulatory phenotypes and functions in response.

TL;DR: The results support the use of PAXgene fixative for the processing of specimens from pancreatic cancers with the potential benefits of improved yields for more amplifiable DNA in low-yield biopsy specimens and its ideal use for amplicon-based NGS assays.

TL;DR: In this article , the De Ritis ratio (DRR), a widely known parameter of liver dysfunction, was incorporated into current or future scoring models to predict early allograft dysfunction and mortality after liver transplantation.

TL;DR: A review of the history of ex-vivo liver machine preservation can be found in this paper , where the authors provide a brief overview of the major drivers of organ discard (age, ischemia time, steatosis etc.) and how this technology may ultimately revert such a trend.