L
Laurence A. Nafie
Researcher at Syracuse University
Publications - 324
Citations - 11297
Laurence A. Nafie is an academic researcher from Syracuse University. The author has contributed to research in topics: Vibrational circular dichroism & Raman optical activity. The author has an hindex of 53, co-authored 322 publications receiving 10738 citations. Previous affiliations of Laurence A. Nafie include Colgate University & University of Southern California.
Papers
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Journal ArticleDOI
Absolute configuration determination of chiral molecules in the solution state using vibrational circular dichroism.
TL;DR: The purpose of the review is to provide an up-to-date perspective on the capability of VCD to solve problems of absolute stereochemistry for chiral molecules primarily in the solution state.
Journal ArticleDOI
Vibrational circular dichroism
Journal ArticleDOI
INFRARED AND RAMAN VIBRATIONAL OPTICAL ACTIVITY: Theoretical and Experimental Aspects
TL;DR: Applications of VOA now include all major classes of biological and pharmaceutical molecules, and its importance as a diagnostic tool will likely grow as the control of molecular chirality increases in research and industrial areas.
Journal ArticleDOI
Determination of absolute configuration of chiral molecules using vibrational optical activity: a review.
TL;DR: The basic principles of the application of VCD to the determination of absolute configuration in chiral molecules are described and the steps required for VCD spectral measurement and calculation are outlined, followed by brief descriptions of recently published papers reporting the determined AC in small organic, pharmaceutical, and natural product molecules.