Laurence Grollet

TL;DR: Data suggest that KSHV could play a role in the pathogenesis of MCD, especially in HIV-infected patients, which is a close association with Kaposi's sarcoma.

TL;DR: Indirect immunofluorescence and immunoblot assays, based on antigens from a latently infected lymphoma cell line, have shown that HHV-8 is not a ubiquitous viral infection in humans.

TL;DR: The clonality status of CD tissues in 34 patients, including 14 patients infected by the human immunodeficiency virus, is reported, and polyclonal VH-JH and V gamma-J gamma rearrangements were detected in the large majority of the cases, irrespective of pathologic subtypes, clinical forms, and HIV status.

TL;DR: The clinical and molecular pattern, as well as the response to therapy suggest that primary effusion lymphoma represents an heterogenous type of virus-induced B-cell lymphoproliferative disorder, sharing pathophysiological features with that induced by the Epstein-Barr virus and occurring in immunocompromised patients.

TL;DR: ZFX was shown to bind the sequences AGGGCCCCA and AGGCCCCGA, located respectively at positions -271 to -263 and -242 to -234 of the HLA-A11 promoter, with similar affinities through its three C-terminal zinc fingers.