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Laurent Mesnard

Researcher at University of Paris

Publications -  118
Citations -  2493

Laurent Mesnard is an academic researcher from University of Paris. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 21, co-authored 82 publications receiving 2034 citations. Previous affiliations of Laurent Mesnard include Cornell University & Pierre-and-Marie-Curie University.

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Improved survival of critically ill cancer patients with septic shock

TL;DR: Earlier ICU admission and antibiotic treatment of critically ill cancer patients with septic shock is associated with higher 30-day survival, and the LOD score change on day 3 as compared to admission is useful for predicting survival.
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Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis

TL;DR: De novo induction of heparin-binding epidermal growth factor–like growth factor in intrinsic glomerular epithelial cells (podocytes) from both mice and humans with RPGN is shown and targeting the HB-EGF–EGFR pathway could also be beneficial in treatment of human RPGN.
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Targeting the Calpain/Calpastatin System as a New Strategy to Prevent Cardiovascular Remodeling in Angiotensin II–Induced Hypertension

TL;DR: Results indicate a critical role for calpains as downstream mediators in Ang II–induced cardiovascular remodeling and, thus, highlight an attractive therapeutic target.
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Early Epithelial Phenotypic Changes Predict Graft Fibrosis

TL;DR: Early phenotypic changes indicative of epithelial-to-mesenchymal transition predict the progression toward interstitial fibrosis in human renal allografts.
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Autoantibodies specific for the phospholipase A2 receptor in recurrent and De Novo membranous nephropathy.

TL;DR: There is evidence that some patients with PLA2R1‐related idiopathic MN and anti‐PLA2 R1 antibodies at the time of transplantation will not develop recurrence and its predictive value should be carefully analyzed in prospective studies.