L
Laurent Zelek
Researcher at University of Paris
Publications - 39
Citations - 1121
Laurent Zelek is an academic researcher from University of Paris. The author has contributed to research in topics: Breast cancer & Prospective cohort study. The author has an hindex of 13, co-authored 39 publications receiving 812 citations. Previous affiliations of Laurent Zelek include Institut national de la recherche agronomique & Sorbonne.
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Prevalence and predictive value of pre-therapeutic sarcopenia in cancer patients: A systematic review.
Frédéric Pamoukdjian,Thierry Bouillet,Vincent Lévy,Michael Soussan,Laurent Zelek,Elena Paillaud +5 more
TL;DR: Pre-therapeutic sarcopenia was significantly and independently associated with post-operative complications, chemotherapy-induced toxicity and poor survival in cancer patients, and has severe consequences for outcomes of cancer patients.
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Relationship between tumor heterogeneity measured on FDG-PET/CT and pathological prognostic factors in invasive breast cancer.
Michael Soussan,Fanny Orlhac,Marouane Boubaya,Laurent Zelek,Marianne Ziol,Véronique Eder,Irène Buvat +6 more
TL;DR: Tumor heterogeneity measured on FDG-PET/CT was higher in invasive breast cancer with poor prognosis pathological factors, and texture analysis might be used, in addition to SUVmax, as a new tool to assess invasive breast cancers aggressiveness.
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Excess body weight and second primary cancer risk after breast cancer: a systematic review and meta-analysis of prospective studies.
Nathalie Druesne-Pecollo,Mathilde Touvier,Emilie Barrandon,Doris S. M. Chan,Teresa Norat,Laurent Zelek,Serge Hercberg,Paule Latino-Martel +7 more
TL;DR: Obesity was associated to significantly increased risks of contralateral breast, breast, and colorectal second primary cancers in women with breast cancer, and this result emphasizes the importance of prevention policies aiming to reduce overweight and obesity prevalence.
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Prospective associations between serum biomarkers of lipid metabolism and overall, breast and prostate cancer risk.
Mathilde His,Laurent Zelek,Mélanie Deschasaux,Camille Pouchieu,Emmanuelle Kesse-Guyot,Serge Hercberg,Pilar Galan,Paule Latino-Martel,Jacques Blacher,Jacques Blacher,Mathilde Touvier +10 more
TL;DR: It is suggested that pre-diagnostic serum levels of T-C, HDL-C and ApoA1 are associated with decreased overall and breast cancer risk, which may have important implications in terms of public health.
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Upfront association of carboplatin plus pemetrexed in patients with brain metastases of lung adenocarcinoma
Olivier Bailon,Kader Chouahnia,Alexandre Augier,Thierry Bouillet,Segolene Billot,Irène Coman,Renata Ursu,Catherine Belin,Laurent Zelek,Gaetan Des Guetz,Christine Levy,Antoine F. Carpentier,Jean-François Morère +12 more
TL;DR: The upfront association of carboplatin plus pemetrexed allows simultaneous treatment of cerebral and systemic disease in patients with NSCLC with newly diagnosed brain metastases and appears to be particularly interesting in terms of radiologic response and overall survival.