Lee Ann Baldridge

TL;DR: It is concluded that immunostaining with antibodies to OCT4 is a useful diagnostic tool in the identification of primary testicular embryonal carcinomas and “usual,” but not spermatocytic, seminomas.

TL;DR: In this paper, the authors analyzed histologically distinct tumor cell populations from the same patient for loss of heterozygosity (LOH) and X chromosome inactivation (in female patients) in 20 patients with small-cell carcinoma of the urinary bladder and concurrent urothelial carcinoma.

TL;DR: Immunohistochemistry of human prostatectomy specimens demonstrated overexpression of the active subunit of NF-κB, p65, and that this occurs at an early stage in the genesis of prostate cancer, and this work supports the rationale for targeting NF-σκB for the prevention and/or treatment of prostatecancer.

TL;DR: Investigation of the immunoreactivity of this tumor to a battery of antibodies shows that TTF-1 expression in small cell carcinoma of the urinary bladder was found in 39% of the tumors, demonstrating that this marker is expressed in smallcell carcinomas other than those of pulmonary origin.

TL;DR: Ritonavir inhibits breast cancer growth in part by inhibiting Hsp90 substrates, including Akt, and its efficacy may be increased by sustained exposure or HSp90 RNA interference.