L
Lei Liu
Researcher at Chinese Academy of Sciences
Publications - 27
Citations - 1957
Lei Liu is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Induced pluripotent stem cell & Embryonic stem cell. The author has an hindex of 17, co-authored 26 publications receiving 1869 citations.
Papers
More filters
Journal ArticleDOI
iPS cells produce viable mice through tetraploid complementation
Xiaoyang Zhao,Wei Li,Zhuo Lv,Lei Liu,Man Tong,Tang Hai,Jie Hao,Chang-long Guo,Qingwen Ma,Liu Wang,Fanyi Zeng,Qi Zhou +11 more
TL;DR: The generation of several iPS cell lines that are capable of generating viable, fertile live-born progeny by tetraploid complementation and confirm that iPS cells can attain true pluripotency that is similar to that of ES cells.
Journal ArticleDOI
Activation of the imprinted Dlk1-Dio3 region correlates with pluripotency levels of mouse stem cells
Lei Liu,Guan-Zheng Luo,Wei Yang,Xiaoyang Zhao,Qinyuan Zheng,Zhuo Lv,Wei Li,Hua-Jun Wu,Liu Wang,Xiu-Jie Wang,Qi Zhou +10 more
TL;DR: A conserved imprinted region of the mouse genome, the Dlk1-Dio3 region, which was activated in fully pluripotent mouse stem cells but repressed in partially pluripotency cells is identified, providing a step forward toward understanding the operating mechanisms during reprogramming to produce iPS cells.
Journal ArticleDOI
Androgenetic haploid embryonic stem cells produce live transgenic mice
Wei Li,Ling Shuai,Ling Shuai,Haifeng Wan,Mingzhu Dong,Meng Wang,Lisi Sang,Chunjing Feng,Guan-Zheng Luo,Tianda Li,Tianda Li,Xin Li,Xin Li,Libin Wang,Qinyuan Zheng,Chao Sheng,Chao Sheng,Hua-Jun Wu,Zhonghua Liu,Lei Liu,Liu Wang,Xiu-Jie Wang,Xiaoyang Zhao,Qi Zhou +23 more
TL;DR: It is shown that mouse androgenetic haploid ES (ahES) cell lines can be established by transferring sperm into an enucleated oocyte and provide a new tool to quickly produce genetic models for recessive traits.
Journal ArticleDOI
Direct reprogramming of Sertoli cells into multipotent neural stem cells by defined factors
Chao Sheng,Qinyuan Zheng,Jianyu Wu,Jianyu Wu,Zhen Xu,Libin Wang,Wei Li,Haijiang Zhang,Xiaoyang Zhao,Lei Liu,Ziwei Wang,Chang-long Guo,Hua-Jun Wu,Zhonghua Liu,Liu Wang,Shigang He,Xiu-Jie Wang,Zhiguo Chen,Zhiguo Chen,Qi Zhou +19 more
TL;DR: It is demonstrated that Sertoli cells derived from mesoderm can be directly converted into a multipotent state that possesses neural stem/progenitor cell properties and is capable of self-renewal and differentiating into glia and electrophysiologically functional neurons.
Journal ArticleDOI
The Gene ncgl2918 Encodes a Novel Maleylpyruvate Isomerase That Needs Mycothiol as Cofactor and Links Mycothiol Biosynthesis and Gentisate Assimilation in Corynebacterium glutamicum
Jie Feng,Yongsheng Che,Johanna Milse,Ya-Jie Yin,Lei Liu,Christian Rückert,Xi-Hui Shen,Su-Wei Qi,Jörn Kalinowski,Shuang-Jiang Liu +9 more
TL;DR: In this paper, it was shown that mycothiol is essential for growth of Corynebacterium glutamicum with gentisate or 3-hydroxybenzoate as carbon sources.