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Lei Liu

Researcher at Chinese Academy of Sciences

Publications -  27
Citations -  1957

Lei Liu is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Induced pluripotent stem cell & Embryonic stem cell. The author has an hindex of 17, co-authored 26 publications receiving 1869 citations.

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iPS cells produce viable mice through tetraploid complementation

TL;DR: The generation of several iPS cell lines that are capable of generating viable, fertile live-born progeny by tetraploid complementation and confirm that iPS cells can attain true pluripotency that is similar to that of ES cells.
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Activation of the imprinted Dlk1-Dio3 region correlates with pluripotency levels of mouse stem cells

TL;DR: A conserved imprinted region of the mouse genome, the Dlk1-Dio3 region, which was activated in fully pluripotent mouse stem cells but repressed in partially pluripotency cells is identified, providing a step forward toward understanding the operating mechanisms during reprogramming to produce iPS cells.
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Androgenetic haploid embryonic stem cells produce live transgenic mice

TL;DR: It is shown that mouse androgenetic haploid ES (ahES) cell lines can be established by transferring sperm into an enucleated oocyte and provide a new tool to quickly produce genetic models for recessive traits.
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Direct reprogramming of Sertoli cells into multipotent neural stem cells by defined factors

TL;DR: It is demonstrated that Sertoli cells derived from mesoderm can be directly converted into a multipotent state that possesses neural stem/progenitor cell properties and is capable of self-renewal and differentiating into glia and electrophysiologically functional neurons.