L
Lei Meng
Researcher at Tianjin Medical University
Publications - 24
Citations - 666
Lei Meng is an academic researcher from Tianjin Medical University. The author has contributed to research in topics: Oxidative stress & Mitochondrial biogenesis. The author has an hindex of 11, co-authored 22 publications receiving 366 citations.
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Journal ArticleDOI
Empagliflozin, a sodium glucose co-transporter-2 inhibitor, alleviates atrial remodeling and improves mitochondrial function in high-fat diet/streptozotocin-induced diabetic rats.
Qingmiao Shao,Lei Meng,Sharen Lee,Gary Tse,Mengqi Gong,Zhiwei Zhang,Jichao Zhao,Yungang Zhao,Guangping Li,Tong Liu +9 more
TL;DR: Empagliflozin can ameliorate atrial structural and electrical remodeling as well as improve mitochondrial function and mitochondrial biogenesis in T2DM, hence may be potentially used in the prevention of T2 DM-related atrial fibrillation.
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Thiazolidinedione use and atrial fibrillation in diabetic patients: a meta-analysis.
Zhiwei Zhang,Xiaowei Zhang,Panagiotis Korantzopoulos,Konstantinos P. Letsas,Gary Tse,Mengqi Gong,Lei Meng,Guangping Li,Tong Liu +8 more
TL;DR: This meta-analysis suggests that TZDs may confer protection against AF in the setting of diabetes mellitus (DM) and can be used as upstream therapy for DM patients to prevent the development of AF.
Journal ArticleDOI
Haematological indices as predictors of atrial fibrillation following isolated coronary artery bypass grafting, valvular surgery, or combined procedures: a systematic review with meta-analysis.
Alexander Weymann,Sadeq Ali-Hasan-Al-Saegh,Aron Frederik Popov,Aron Frederik Popov,Aron Frederik Popov,Anton Sabashnikov,Seyed Jalil Mirhosseini,Tong Liu,Gary Tse,Mohammad Reza Lotfaliani,Azam Ghanei,Luca Testa,Fabrizio D'Ascenzo,Umberto Benedetto,Hamidreza Dehghan,Leonardo Roever,Michel Pompeu Barros de Oliveira Sá,William L. Baker,Senol Yavuz,M. Zeriouh,Ahmed Mashhour,Luis Nombela-Franco,Jae Sik Jang,Lei Meng,Mengqi Gong,Abhishek Deshmukh,Tullio Palmerini,Cecilia Linde,Krzysztof J. Filipiak,Giuseppe Biondi-Zoccai,Giuseppe Biondi-Zoccai,Hugh Calkins,Gregg W. Stone +32 more
TL;DR: Haematological indices in CBC tests with atrial fibrillation following isolated coronary artery bypass graft, isolated valvular surgery, or a combination of these treatments may predict the risk of POAF before surgery.
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Hyperglycemia Induces Endoplasmic Reticulum Stress in Atrial Cardiomyocytes, and Mitofusin-2 Downregulation Prevents Mitochondrial Dysfunction and Subsequent Cell Death.
Ming Yuan,Mengqi Gong,Mengqi Gong,Zhiwei Zhang,Lei Meng,Gary Tse,Yungang Zhao,Qiankun Bao,Yue Zhang,Meng Yuan,Xing Liu,Guangping Li,Tong Liu +12 more
TL;DR: Mfn2 plays an important role in high glucose-induced ER stress in atrial cardiomyocytes, and Mfn2 silencing prevents mitochondrial Ca2+ overload-mediated mitochondrial dysfunction, thereby decreasing ER stress-mediatedCardiomyocyte cell death.
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Prediction of New-Onset and Recurrent Atrial Fibrillation by Complete Blood Count Tests: A Comprehensive Systematic Review with Meta-Analysis
Alexander Weymann,Sadeq Ali-Hasan-Al-Saegh,Anton Sabashnikov,Aron Frederik Popov,Aron Frederik Popov,Seyed Jalil Mirhosseini,Tong Liu,Mohammad Reza Lotfaliani,Michel Pompeu Barros de Oliveira Sá,William L. Baker,Senol Yavuz,Mohamed Zeriouh,Jae-Sik Jang,Hamidreza Dehghan,Lei Meng,Luca Testa,Fabrizio D'Ascenzo,Umberto Benedetto,Gary Tse,Luis Nombela-Franco,Pascal M. Dohmen,Pascal M. Dohmen,Abhishek Deshmukh,Cecilia Linde,Giuseppe Biondi-Zoccai,Gregg W. Stone,Hugh Calkins +26 more
TL;DR: Hematological parameters have significant ability to predict occurrence and recurrence of AF, and it is recommended to add the CBC test to the diagnostic modalities of AF in clinical practice.