L
Leonor Pássaro
Publications - 5
Citations - 49
Leonor Pássaro is an academic researcher. The author has contributed to research in topics: Pseudomonas aeruginosa & Tazobactam. The author has an hindex of 3, co-authored 5 publications receiving 17 citations.
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Journal ArticleDOI
In vitro activity of ceftolozane-tazobactam against Enterobacterales and Pseudomonas aeruginosa causing urinary, intra-abdominal and lower respiratory tract infections in intensive care units in Portugal: The STEP multicenter study
Sergio García-Fernández,María García-Castillo,José Melo-Cristino,Margarida F Pinto,Elsa Gonçalves,Valquíria Alves,Ana Raquel Vieira,Elmano Ramalheira,Luísa Sancho,José Diogo,Rui Seabra Ferreira,Daniela A. Fossato da Silva,Catarina Chaves,Leonor Pássaro,Laura Paixão,Rafael Cantón +15 more
TL;DR: These microbiological results reinforce ceftolozane-tazobactam as a therapeutic option in ICU patients with UTI, IAI or LRTI due to P. aeruginosa or Enterobacterales isolates, but not for carbapenemase producers.
Journal ArticleDOI
Distinct epidemiology and resistance mechanisms affecting ceftolozane/tazobactam in Pseudomonas aeruginosa isolates recovered from ICU patients in Spain and Portugal depicted by WGS.
Marta Hernández-García,María García-Castillo,Sergio García-Fernández,José Melo-Cristino,Margarida F Pinto,Elsa Gonçalves,Valquíria Alves,Ana Raquel Vieira,Elmano Ramalheira,Luísa Sancho,José Diogo,Rui Ferreira,Tânia F.C.V. Silva,Catarina Chaves,Germán Bou,Emilia Cercenado,Mercedes Delgado-Valverde,Antonio Oliver,Cristina Pitart,Jesús Rodríguez-Lozano,Nuria Tormo,João Romano,Leonor Pássaro,Laura Paixão,Diego López-Mendoza,Jazmín Díaz-Regañón,Rafael Cantón,Superior study groups +27 more
TL;DR: An extensive virulome was identified in all P. aeruginosa isolates, particularly in carbapenemase-producing strains, and ceftolozane/tazobactam resistance was significantly associated with GES-13 and VIM-type carbapanemase production.
Journal ArticleDOI
Confronting Ceftolozane-Tazobactam Susceptibility in Multidrug-Resistant Enterobacterales Isolates and Whole-Genome Sequencing Results (STEP Study).
Marta Hernández-García,Sergio García-Fernández,María García-Castillo,José Melo-Cristino,Margarida F Pinto,Elsa Gonçalves,Valquíria Alves,Eliana Costa,Elmano Ramalheira,Luísa Sancho,José Diogo,Rui Ferreira,Tânia F.C.V. Silva,Catarina Chaves,Leonor Pássaro,Laura Paixão,João Romano,Rafael Cantón +17 more
TL;DR: WGS is a powerful tool for typing characterization and microbiological study of MDR-Enterobacterales pathogens and carbapenemase genes are associated with C/T-resistance in Klebsiella spp.
Journal ArticleDOI
Presence of Chromosomal crpP-like Genes Is Not Always Associated with Ciprofloxacin Resistance in Pseudomonas aeruginosa Clinical Isolates Recovered in ICU Patients from Portugal and Spain.
Marta Hernández-García,María García-Castillo,Sergio García-Fernández,Diego López-Mendoza,Jazmín Díaz-Regañón,João Marcos Travassos Romano,Leonor Pássaro,Laura Paixão,Rafael Cantón +8 more
TL;DR: In this article, the presence of crpP-genes and other mechanisms involved in quinolone resistance in MDR/XDR-Pseudomonas aeruginosa isolates (n = 55) with both ceftolozane-tazobactam susceptible or resistant profiles recovered from intensive care unit patients during the STEP (Portugal) and SUPERIOR (Spain) surveillance studies was investigated by whole genome sequencing.
Journal ArticleDOI
In vitro characterization of Pseudomonas aeruginosa recovered in Portugal from low respiratory tract infections in ICU patients (STEP Study).
Marta Hernández-García,Sergio García-Fernández,María García-Castillo,Leonor Pássaro,Rafael Cantón,José Melo-Cristino,Margarida Pinto,Cristina Marcelo,Helena Peres,Isabel Lourenço,Isabel Peres,João Carlos Marques,Odete Chantre,Teresa Pina,Laboratório de Microbiologia,Serviço de Patologia Clínica,Elsa M. Gonçalves,Cristina Toscano,Valquíria Alves,Serviço de Microbiologia,Manuela Ribeiro,Eliana Costa,Ana Raquel Vieira,Serviço Patologia Clínica,Sonia Maria Soares Ferreira,Raquel Diaz,Elmano Ramalheira,Sandra Schäfer,Luísa Tancredo,Luísa Sancho,Ana Maria Rodrigues,José Diogo,Rui Ferreira,Helena Ramos,Tânia F.C.V. Silva,Daniela Gomes da Silva,Catarina Chaves,C. Queiroz,Altair Nabiev,Laura Paixão,João Marcos Travassos Romano,Carolina Moura,María García del Castillo +42 more
TL;DR: In this paper, the authors characterized the distribution and mechanisms involved in ceftolozane/tazobactam (C/T) resistance in Pseudomonas aeruginosa isolates recovered from intensive care units (ICUs) in Portugal as part of the STEP surveillance study.