L
Leslie Samuel
Researcher at Aberdeen Royal Infirmary
Publications - 86
Citations - 2224
Leslie Samuel is an academic researcher from Aberdeen Royal Infirmary. The author has contributed to research in topics: Colorectal cancer & Capecitabine. The author has an hindex of 23, co-authored 82 publications receiving 1885 citations. Previous affiliations of Leslie Samuel include Western General Hospital & University of Cambridge.
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Journal ArticleDOI
Randomized Controlled Clinical Effectiveness Trial of Cognitive Behavior Therapy Compared With Treatment As Usual for Persistent Insomnia in Patients With Cancer
Colin A. Espie,Leanne Fleming,Jim Cassidy,Leslie Samuel,L.M. Taylor,Craig White,Neil J. Douglas,Heather M. Engleman,Heidi Louise Kelly,James Paul +9 more
TL;DR: CBT for insomnia may be both clinically effective and feasible to deliver in real world practice, as investigated by oncology nurses.
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Does aqueous or sucralfate cream affect the severity of erythematous radiation skin reactions? A randomised controlled trial.
Mary Wells,Maureen Macmillan,Gillian M. Raab,Sheila K. Macbride,Nancy Bell,Karen MacKinnon,Hugh MacDougall,Leslie Samuel,Alastair J. Munro +8 more
TL;DR: There is no evidence to support the prophylactic application of either of the creams tested for the prevention of radiation skin reactions, and the results show that it is possible to predict which patients are at greatest risk of skin reactions.
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A randomised cross-over trial comparing patient preference for oral capecitabine and 5-fluorouracil/leucovorin regimens in patients with advanced colorectal cancer
TL;DR: Capecitabine clearly represents an effective, well-tolerated oral alternative to i.v. 5-FU/LV and is confirmed that the majority of patients with MCRC prefer oral to i-v.
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EXTRA-A Multicenter Phase II Study of Chemoradiation Using a 5 Day per Week Oral Regimen of Capecitabine and Intravenous Mitomycin C in Anal Cancer
Rob Glynne-Jones,Helen Meadows,Susan Wan,Simon Gollins,Martin Leslie,Edward A. Levine,Alec McDonald,A. Sun Myint,Leslie Samuel,David Sebag-Montefiore +9 more
TL;DR: Capecitabine with MMC and RT in with patients anal carcinoma is well tolerated, with minimal toxicity and acceptable compliance, and recommends testing this schedule in future national Phase III studies in anal cancer.
Journal ArticleDOI
Modifiable and fixed factors predicting quality of life in people with colorectal cancer
Nicola M Gray,Susan Hall,Susan Browne,Una Macleod,Elizabeth Mitchell,Amanda J Lee,Marie Johnston,Sally Wyke,Leslie Samuel,David Weller,Neil C Campbell +10 more
TL;DR: Most factors affecting QoL are modifiable, especially symptoms (fatigue, anorexia, dyspnoea) and depression, and Beliefs about illness are also important.