Leslie W. Glustrom

TL;DR: This work estimates that the life cycle effects of coal and the waste stream generated are costing the U.S. public a third to over one‐half of a trillion dollars annually, and conservatively doubles to triples the price of electricity from coal per kWh generated, making wind, solar, and other forms of nonfossil fuel power generation, along with investments in efficiency and electricity conservation methods, economically competitive.

TL;DR: The structure reported here provides a foundation for understanding the mechanism by which Cdc13 recognizes GT-rich heterogeneous sequences with both unusually strong affinity and high specificity, and indicates that molecular recognition of extended single-stranded nucleic acids may proceed via a folding-type mechanism rather than resulting from specific patterns of hydrogen bonds.

TL;DR: The structure of the soluble, N-terminal domain of 3A (3A-N) is determined using NMR spectroscopy, and it is shown that 3A- N exists as a symmetric dimer, and each monomer consists of an alpha-helical hairpin with unstructured, yet functional,N- and C termini.

TL;DR: This study has found that a telomere-binding protein exhibits a degree of specificity for ssDNA that is finely tuned for its function, which includes specificity for G-rich sequences with some tolerance for substitution.