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Letizia Mattii

Researcher at University of Pisa

Publications -  86
Citations -  1317

Letizia Mattii is an academic researcher from University of Pisa. The author has contributed to research in topics: RHOA & Receptor. The author has an hindex of 20, co-authored 80 publications receiving 1129 citations.

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Immunohistochemical analysis of myenteric ganglia and interstitial cells of Cajal in ulcerative colitis

TL;DR: Quantitative variations of myenteric neuro‐glial cells and ICC indicate considerable alterations of the colonic neuromuscular compartment in the setting of mucosal inflammation associated with UC, and provide a morphological basis for better understanding the motor abnormalities often observed in UC patients.
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Expression of C-type natriuretic peptide and its receptor NPR-B in cardiomyocytes.

TL;DR: Results showed that cardiac cells as well as endothelial cells were able to produce CNP, suggesting that the heart is actively involved in the production of CNP.
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Morpho-functional characterization of human mesenchymal stem cells from umbilical cord blood for potential uses in regenerative medicine.

TL;DR: UCB-derived MSCs were proved to grow on biodegradable microfiber meshes; additionally, they were able to differentiate toward mature osteoblasts when cultured inside human plasma clots, suggesting their potential application in orthopedic surgery.
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Interaction of human gingival fibroblasts with PVA/gelatine sponges.

TL;DR: The in situ creation of a biological matrix by human fibroblasts together with the ability to produce growth factor TGF-beta1 and the intracellular signal transduction molecule RhoA suggests that this kind of PVA/gelatine sponge may represent a suitable support for in vitro extracellular matrix production and connective tissue regeneration.
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Nutlin-loaded magnetic solid lipid nanoparticles for targeted glioblastoma treatment.

TL;DR: Nut-Mag-SLNs represent a promising multifunctional nanoplatform for the treatment of glioblastoma multiforme and showed good colloidal stability, the ability to cross an in vitro blood–brain barrier model, and a superior pro-apoptotic activity toward gliOBlastoma cells with respect to the free drug.