L
Letizia Mattii
Researcher at University of Pisa
Publications - 86
Citations - 1317
Letizia Mattii is an academic researcher from University of Pisa. The author has contributed to research in topics: RHOA & Receptor. The author has an hindex of 20, co-authored 80 publications receiving 1129 citations.
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Journal ArticleDOI
Immunohistochemical analysis of myenteric ganglia and interstitial cells of Cajal in ulcerative colitis
Nunzia Bernardini,Cristina Segnani,Chiara Ippolito,Roberto De Giorgio,Rocchina Colucci,Maria Simonetta Faussone-Pellegrini,Massimo Chiarugi,Daniela Campani,Maura Castagna,Letizia Mattii,Corrado Blandizzi,Amelio Dolfi +11 more
TL;DR: Quantitative variations of myenteric neuro‐glial cells and ICC indicate considerable alterations of the colonic neuromuscular compartment in the setting of mucosal inflammation associated with UC, and provide a morphological basis for better understanding the motor abnormalities often observed in UC patients.
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Expression of C-type natriuretic peptide and its receptor NPR-B in cardiomyocytes.
S. Del Ry,Manuela Cabiati,Federico Vozzi,B. Battolla,Chiara Caselli,Francesca Forini,Cristina Segnani,Tommaso Prescimone,Daniela Giannessi,Letizia Mattii +9 more
TL;DR: Results showed that cardiac cells as well as endothelial cells were able to produce CNP, suggesting that the heart is actively involved in the production of CNP.
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Morpho-functional characterization of human mesenchymal stem cells from umbilical cord blood for potential uses in regenerative medicine.
Serena Barachini,Luisa Trombi,Serena Danti,Delfo D'Alessandro,B. Battolla,Annalisa Legitimo,Claudia Nesti,I Mucci,Mario D’Acunto,Maria Grazia Cascone,Luigi Lazzeri,Letizia Mattii,Rita Consolini,Mario Petrini +13 more
TL;DR: UCB-derived MSCs were proved to grow on biodegradable microfiber meshes; additionally, they were able to differentiate toward mature osteoblasts when cultured inside human plasma clots, suggesting their potential application in orthopedic surgery.
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Interaction of human gingival fibroblasts with PVA/gelatine sponges.
Stefania Moscato,Letizia Mattii,Delfo D'Alessandro,Maria Grazia Cascone,Luigi Lazzeri,L. P. Serino,Amelio Dolfi,Nunzia Bernardini +7 more
TL;DR: The in situ creation of a biological matrix by human fibroblasts together with the ability to produce growth factor TGF-beta1 and the intracellular signal transduction molecule RhoA suggests that this kind of PVA/gelatine sponge may represent a suitable support for in vitro extracellular matrix production and connective tissue regeneration.
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Nutlin-loaded magnetic solid lipid nanoparticles for targeted glioblastoma treatment.
Agostina Grillone,Matteo Battaglini,Matteo Battaglini,Stefania Moscato,Letizia Mattii,César de Julián Fernández,Alice Scarpellini,Mario Giorgi,Edoardo Sinibaldi,Gianni Ciofani,Gianni Ciofani +10 more
TL;DR: Nut-Mag-SLNs represent a promising multifunctional nanoplatform for the treatment of glioblastoma multiforme and showed good colloidal stability, the ability to cross an in vitro blood–brain barrier model, and a superior pro-apoptotic activity toward gliOBlastoma cells with respect to the free drug.