L
Li-Lin Du
Researcher at Tsinghua University
Publications - 79
Citations - 9165
Li-Lin Du is an academic researcher from Tsinghua University. The author has contributed to research in topics: Schizosaccharomyces pombe & DNA repair. The author has an hindex of 29, co-authored 79 publications receiving 7517 citations. Previous affiliations of Li-Lin Du include Scripps Research Institute & Yale University.
Papers
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Journal ArticleDOI
Identification of Methylosome Components as Negative Regulators of Plant Immunity Using Chemical Genetics
Shuai Huang,Aruna D. Balgi,Yaping Pan,Meng Li,Xiao-Ran Zhang,Li-Lin Du,Ming Zhou,Michel Roberge,Xin Li +8 more
TL;DR: The successful implementation of a high-throughput chemical genetic screen and the identification of a small-molecule compound affecting plant immunity indicate that chemical genetics is a powerful tool to study whole-organism plant defense pathways.
Journal ArticleDOI
Molecular and structural mechanisms of ZZ domain-mediated cargo selection by Nbr1.
Ying-Ying Wang,Jianxiu Zhang,Xiao-Man Liu,Yulu Li,Jianhua Sui,Meng-Qiu Dong,Keqiong Ye,Li-Lin Du +7 more
TL;DR: In this paper, a single-domain bispecific mechanism of autophagy cargo recognition, elucidate its underlying structural basis, and expand the understanding of ZZ domain-mediated protein-protein interactions.
Posted ContentDOI
A cloning-free method for CRISPR/Cas9-mediated genome editing in fission yeast
TL;DR: This gap-repair-based and cloning-free CRISPR/Cas9 procedure permits rapid and efficient point mutation knock-in, endogenous N-terminal tagging, and genomic sequence deletion in fission yeast.
Book ChapterDOI
Purification and properties of a GTPase-activating protein for yeast Rab GTPases.
Li-Lin Du,Peter Novick +1 more
Journal ArticleDOI
Mck1 defines a key S-phase checkpoint effector in response to various degrees of replication threats
Xiaoli Li,Xuejiao Jin,Sushma Sharma,Xiaojing Liu,Jiaxin Zhang,Yanling Niu,Jiani Li,Zhen Li,Jingjing Zhang,Qinhong Cao,Wenya Hou,Li-Lin Du,Beidong Liu,Huiqiang Lou +13 more
TL;DR: Findings reveal the division-of-labor between Mck1 and Dun1 at the S-phase checkpoint pathway to fine-tune dNTP homeostasis and help eukaryotic cells respond appropriately to different levels of replication threats.