L
Li Yang
Researcher at Sichuan University
Publications - 371
Citations - 6789
Li Yang is an academic researcher from Sichuan University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 35, co-authored 295 publications receiving 4474 citations.
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Journal ArticleDOI
Immunotherapy of tumors with xenogeneic endothelial cells as a vaccine
Yu Quan Wei,Qing Ru Wang,Xia Zhao,Li Yang,Ling Tian,You Lu,Bin Kang,Chong Jiu Lu,Mei Juan Huang,Yan Yan Lou,Fei Xiao,Qiu Ming He,Jing Mei Shu,Xing Jiang Xie,Yun Qiu Mao,Shong Lei,Feng Luo,Li Qun Zhou,Chong En Liu,Hao Zhou,Yu Jiang,Feng Peng,Liang Ping Yuan,Qiu Li,Yang Wu,Ji Yan Liu +25 more
TL;DR: It is shown that immunotherapy of tumors using fixed xenogeneic whole endothelial cells as a vaccine was effective in affording protection from tumor growth, inducing regression of established tumors and prolonging survival of tumor-bearing mice.
Journal ArticleDOI
Immunogene therapy of tumors with vaccine based on xenopus homologous vascular endothelial growth factor as a model antigen
Yu Quan Wei,Mei Juan Huang,Li Yang,Xia Zhao,Ling Tian,You Lu,Jing Mei Shu,Chong Jiu Lu,Ting Niu,Bin Kang,Yun Qiu Mao,Fen Liu,Yan Jun Wen,Shong Lei,Feng Luo,Li Qun Zhou,Feng Peng,Yu Jiang,Ji Yan Liu,Hao Zhou,Qing Ru Wang,Qiu Ming He,Fei Xiao,Yan Yan Lou,Xing Jiang Xie,Qiu Li,Yang Wu,Zhen Yu Ding,Bin Hu,Min Hu,Wei Zhang +30 more
TL;DR: It is found that immunogene tumor therapy with a vaccine based on XVEGF was effective at both protective and therapeutic antitumor immunity in several tumor models in mice, and may provide a vaccine strategy for cancer therapy through the induction of autoimmunity against the growth factors associated with tumor growth.
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Silencing of pkm2 increases the efficacy of docetaxel in human lung cancer xenografts in mice.
Huashan Shi,Dan Li,Jing Zhang,Yongsheng Wang,Li Yang,Hailong Zhang,Xianhuo Wang,Bo Mu,Wei Wang,Yu Ma,Fuchun Guo,Yuquan Wei +11 more
TL;DR: The effects of combining shRNA targeting PKM2 and docetaxel on human A549 lung carcinoma cells both in vivo and in vitro suggest that targeting tumor glycolysis can increase the efficacy of chemotherapy.
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Inflammation-Responsive Drug-Loaded Hydrogels with Sequential Hemostasis, Antibacterial, and Anti-Inflammatory Behavior for Chronically Infected Diabetic Wound Treatment.
TL;DR: In this paper, a dual-responsive (pH and reactive oxygen species (ROS)) hydrogel was prepared to realize drug release properties under inflammatory stimulation by grafting 3-carboxy-phenylboronic acid to the gelatin molecular backbone and cross-linking with poly(vinyl alcohol).
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Synergistic effects of antimicrobial peptide DP7 combined with antibiotics against multidrug-resistant bacteria.
Xiaozhe Wu,Zhan Li,Xiaolu Li,Yaomei Tian,Yingzi Fan,Chaoheng Yu,Bailing Zhou,Yi Liu,Rong Xiang,Li Yang +9 more
TL;DR: AMP DP7 plus the antibiotic AZT or VAN is more effective, especially against highly antibiotic-resistant strains, particularly against highly resistant strains carrying more than two AZT-resistance genes.